compound 14n [PMID: 25589934]

Ligand id: 9423

Name: compound 14n [PMID: 25589934]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 135.03
Molecular weight 418.04
XLogP 2.81
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[4-(3-amino-2H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-5-chloro-2-fluorobenzenesulfonamide
Database Links
BindingDB Ligand 50443628
ChEMBL Ligand CHEMBL3092468
GtoPdb PubChem SID 328083523
PubChem CID 71506845
Search Google for chemical match using the InChIKey DDKHTWASHUKHLD-UHFFFAOYSA-N
Search Google for chemicals with the same backbone DDKHTWASHUKHLD
Search UniChem for chemical match using the InChIKey DDKHTWASHUKHLD-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone DDKHTWASHUKHLD
Comments
Compound 14n is an inhibitor of serum/glucocorticoid regulated kinases, with moderate selectivity for SGK1 and SGK2 over SGK3[1].