telotristat ethyl

Ligand id: 9490

Name: telotristat ethyl

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 131.17
Molecular weight 574.17
XLogP 6.32
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2017))
IUPAC Name
ethyl (2S)-2-amino-3-[4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl]phenyl]propanoate
International Nonproprietary Names
INN number INN
9324 telotristat
Synonyms
LX-1606 | LX1606 | Xermelo®
Database Links
CAS Registry No. 1033805-22-9 (source: PubChem)
ChEMBL Ligand CHEMBL2105695
PubChem CID 25181577
Search Google for chemical match using the InChIKey MDSQOJYHHZBZKA-GBXCKJPGSA-N
Search Google for chemicals with the same backbone MDSQOJYHHZBZKA
Search PubMed clinical trials telotristat
Search PubMed titles telotristat
Search PubMed titles/abstracts telotristat
Search UniChem for chemical match using the InChIKey MDSQOJYHHZBZKA-GBXCKJPGSA-N
Search UniChem for chemicals with the same backbone MDSQOJYHHZBZKA
Comments
Telotristat ethyl is an oral tryptophan hydroxylase inhibitor. Telotristat ethyl is the USAN, the INN is telotristat (represented in PubChem CID 25025298.