BMS-986020

Ligand id: 9498

Name: BMS-986020

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 101.66
Molecular weight 482.18
XLogP 9.24
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-[4-[4-[3-methyl-4-[[(1R)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]cyclopropane-1-carboxylic acid
Synonyms
AM152 | AP-3152 free acid
Database Links
GtoPdb PubChem SID 329968437
PubChem CID 49792850
Search Google for chemical match using the InChIKey GQBRZBHEPUQRPL-LJQANCHMSA-N
Search Google for chemicals with the same backbone GQBRZBHEPUQRPL
Search UniChem for chemical match using the InChIKey GQBRZBHEPUQRPL-LJQANCHMSA-N
Search UniChem for chemicals with the same backbone GQBRZBHEPUQRPL
Comments
BMS-986020 is an investigational lysophosphatidic acid 1 (LPA1) receptor antagonist [2]. Claimed as Compound 1-1 in patent WO2010141768 [1], and this document contains extensive in vitro characterisation and in vivo anti-fibrotic efficacy in various animal models of fibrosis.