eCF309

Ligand id: 9571

Name: eCF309

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 140.13
Molecular weight 383.17
XLogP 0.8
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-[4-amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine
Synonyms
compound 12 [Fraser et al., 2016] [1] | eCF-309
Database Links
BindingDB Ligand 200300
GtoPdb PubChem SID 336446957
PubChem CID 122163152
Search Google for chemical match using the InChIKey PSICWGWNIOOULV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone PSICWGWNIOOULV
Search UniChem for chemical match using the InChIKey PSICWGWNIOOULV-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone PSICWGWNIOOULV
Comments
eCF309 is a low nanomolar potency, selective and cell-permeable mTOR inhibitor [1].