CC-220

Ligand id: 9618

Name: CC-220

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 88.18
Molecular weight 449.2
XLogP 1.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(3S)-3-[7-[[4-(morpholin-4-ylmethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
Synonyms
compound 6 [PMID: 28425720] | iberdomide (proposed INN)
Database Links
PubChem CID 67335295
RCSB PDB Ligand 8W7
Search Google for chemical match using the InChIKey IXZOHGPZAQLIBH-NRFANRHFSA-N
Search Google for chemicals with the same backbone IXZOHGPZAQLIBH
Search UniChem for chemical match using the InChIKey IXZOHGPZAQLIBH-NRFANRHFSA-N
Search UniChem for chemicals with the same backbone IXZOHGPZAQLIBH
Comments
CC-220 is a novel cereblon modulator [3], functionally akin to lenalidomide and pomalidomide.