esaxerenone

Ligand id: 9894

Name: esaxerenone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 96.78
Molecular weight 466.12
XLogP 4.35
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-(2-hydroxyethyl)-4-methyl-N-(4-methylsulfonylphenyl)-5-[2-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
International Nonproprietary Names
INN number INN
10230 esaxerenone
Synonyms
CS-3150 | XL-550
Comments
Selective antagonist of the mineralocorticoid receptor that has progressed to clinical trials in a number of indications [1]. This ligand was an author pre-publication alert.
Database Links
CAS Registry No. 1632006-28-0
ChEMBL Ligand CHEMBL2181932
GtoPdb PubChem SID 363894188
PubChem CID 25052023
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