The IUPHAR Guide to PHARMACOLOGY complete ligand list

Includes therapeutic monoclonal antibodies.

A  B  C  D  E  F  G  I  L  M  N  O  P  Q  R  S  T  U  V  X  Y 

Ligand name ID Synonyms
A Back to top
abagovomab 8265 ACA125, MEN-2234
abatacept 6891 BMS-188667, CTLA4-IgG4m, Orencia®, RG-1046, RG-2077
abciximab 6584 7E3 antibody, antiGPIIBIIIa, C7E3, ReoPro®
adalimumab 4860 D2E7, FKB327, Humira®
aducanumab 8325 BART, BIIB-037, BIIB037
aflibercept 6786 AVE0005, Eylea®, VEGF Trap, Zaltrap®, ziv-aflibercept
alefacept 6787 Amevive®, BG 9273, BG 9712, BG-9273, BG-9712, Lfa3Tip
alemtuzumab 6770 campath 1H, Campath®, campath-1H, Lemtrada®
alirocumab 6744 Praluent®, REGN727, SAR-236553, SAR236553
amatuximab 7750 MORAb-009
AMG820 9106
andecaliximab 9510 GS-5745
anifrolumab 8258 MDX-1333, MEDI-546
anti-ILT7 antibody 9124
atezolizumab 7990 MPDL3280A, Tecentriq®
avelumab 8735 Bavencio®, MSB-0010718C, MSB0010718C
 
B Back to top
bapineuzumab 6930 3D-6, AAB-001
basiliximab 6879 CHI-621, L04AC02, SDZ-CHI-621, Simulect®
bavituximab 8002 Tarvacin ch3G4
begelomab 8691 Begendina&rg; (proprietary name), BT 5/9, SAND 26
belatacept 6892 BMS-224818, LEA29Y, Nulojix®
belimumab 6887 Benlysta®, hBlySmAb-1.1, lymphostat-B
benralizumab 7674 BIW-8405, Fasenra®, KHK4563, MEDI-563
bevacizumab 6771 Avastin®, rhuMAb-VEGF
BGB-A317 9592
bimagrumab 8086 BYM-338, BYM338
bimekizumab 9411 CA028_0496, CDP4940, gL7gH9, UCB-4940, UCB4940, Zu-G1
blinatumomab 7384 Blincyto®, bscCD19xCD3, MEDI-538, MT-103, MT103
BMS-986016 9536 ONO-4482
bococizumab 7730 PF-04950615, RN-316, RN316
BPS-804 9202 BPS 804, BPS804
brazikumab 9293 AMG 139, AMG-139, MEDI2070
brentuximab vedotin 6772 Adcetris®, anti-CD30 ADC SGN-35, SGN 35
briakinumab 9213 ABT-874, J-695, J695, Ozespa
brodalumab 7540 AMG-827, AMG827, Kyntheum®, Lumicef®, Siliq®
brolucizumab 8713 ESBA-1008, ESBA1008
burosumab 9292 KRN-23, KRN23, N5KG1_C10_LH, UX-023, UX023
 
C Back to top
cabiralizumab 9107 BMS-986227, FPA-008, FPA008
canakinumab 6773 ACZ 885, ACZ885, Ilaris®
caplacizumab 9123 ALX-0081, anti-vWF Nanobody
capromab 6878 capromab pendetide, CYT-351, CYT-356, Indium In 111 capromab, ProstaScint®
carotuximab 9098 c-SN6j, TRC-105, TRC105
catumaxomab 7385 L01XC09, Removab®
certolizumab pegol 6774 CDP870, Cimzia®, PHA 738144
cetuximab 6882 C225, Erbitux®, IMC-225, IMC-C225
clazakizumab 9195 ALD-518, ALD518, BMS-945429
codrituzumab 8406 GC33, RG-7686, RG7686, RO-5137382, RO5137382
crenezumab 6934 MABT-5102A, Mabt5102A
crotedumab 9614 REGN-1193, REGN1193
 
D Back to top
daclizumab 6880 L04AC01, RO-24-7375, Ro-247375, Zenapax®
daratumumab 7395 3003-005, Darzalex®, HuMax-CD38, JNJ-54767414
dectrekumab 8714 QAX-576, QAX576
demcizumab 8451 OMP-21M18
denosumab 6886 AMG-162, M05BX04, Prolia®, Xgeva®
depatuxizumab mafodotin 7970 ABT-414
dezamizumab 8255 GSK-2398852, GSK2398852
dinutuximab 7979 APN-311, Ch14.18, MAb-14.18, Unituxin®
domagrozumab 9096 clone OGD1.0.0, PF-06252616, PF06252616
dupilumab 7574 Dupixent®, REGN668, SAR231893
durvalumab 7985 anti-B7H1 monoclonal antibody, Imfinzi®, MEDI-4736, MEDI4736
dusigitumab 7749 MEDI-573
 
E Back to top
eculizumab 6884 h5G1.1, h5G1.1VHC, Soliris®
edrecolomab 7984 17-1A, PANOREX® (proposed trade name)
efalizumab 6593 anti alphaL integrin, antiCD11 alpha, hu1124, Raptiva®
eldelumab 9047 BMS-936557, MDX-1100
elezanumab 9290 ABT-555, AE12-1Y-QL
elgemtumab 8715 LJM716, NVS201010
elotuzumab 8361 BMS-901608, Empliciti®, HuLuc63
emactuzumab 8944 RG7155, RO5509554
emapalumab 9295 Ni-0501, NI-0501
emibetuzumab 7748 LA480, LY-2875358, LY2875358
enoblituzumab 9589 MGA-271, MGA271
enokizumab 8934 7F3com-2H2, MEDI-528, MEDI528
epratuzumab 8088 90Y-DOTA-hLL2, 90Y-epratuzumab tetraxetan, 90Y-hLL2, AMG-412, IMMU-hLL2, LymphoCide® (proposed proprietary name)
erenumab 9250 Aimovig (proposed trade name), AMG 334, AMG-334
etanercept 6789 Enbrel®, Rhu Tnfr:Fc, TNFR-Fc, TNR 001
etaracizumab 6596 etaratuzumab, hLM60, MEDI-522
etrolizumab 8407 PRO145223, RG-7413, RG7413, rhuMAb Beta7
evinacumab 8717 REGN1500
evolocumab 7343 AMG-145, AMG145, NN7415, Repatha®
 
F Back to top
fasinumab 8965 REGN475, SAR164877
fezakinumab 9281 ILV-094
fibatuzumab 8925 KB-004, KB004
fremanezumab 9208 LBR-101, PF-04427429, RN307, TEV-48125
fresolimumab 8264 GC1008, PET1073G12
fulranumab 8964 AMG-403, JNJ-42160443
 
G Back to top
galcanezumab 8967 clone III, LY-2951742, LY2951742
gantenerumab 6933 R-1450, RG-1450, Ro-4909832
gemtuzumab ozogamicin 6775 CDP 771, CMA 676, hP67.6-calicheamicin, Mylotarg®, WAY-CMA 676
gevokizumab 7394 Xoma 052, XOMA-052
gimsilumab 9624 MORAb-022
girentuximab 7987 cG250, G250, Rencarex® (proposed proprietary name), WX-G250
glembatumumab vedotin 8926 CDX-011, CR011-vcMMAE
golimumab 6776 CNTO-148, CNTO148, Simponi®
GSK3050002 9623 E6071, KANAb071
guselkumab 7998 CNTO-1959, Tremfya®
 
I Back to top
ibritumomab tiuxetan 6777 IDEC-2B8, IDEC-Y2B8-yttrium ibritumomab tiuxetan, NSC-715848, Zevalin®
idarucizumab 8298 BI 655075, Praxbind®
IGN523 8737
IMAB362 9209
IMCgp100 7378
indusatumab vedotin 8718 5F9vcMMAE, MLN-0264, MLN0264
inebilizumab 7992 HB12, MEDI 551, MEDI-551, MEDI551
infliximab 5004 cA2, Inflectra®, Remicade®, Remsima®, SB2, TA-650
inotuzumab ozogamicin 8266 Besponsa®, CMC-544
ipilimumab 6888 MDX-010, MDX-101, MDX-CTLA-4, Yervoy®
isatuximab 8719 ch38SB19, hu38SB19, SAR-650984, SAR650984
istiratumab 8931 MM-111
itolizumab 9421 Alzumab®, T1h
ixekizumab 7541 LY-2439821, Taltz®
 
L Back to top
labetuzumab 8251 CEACIDE®, hMN14
labetuzumab govitecan 8252 hMN-14-SN-38, hMN-14-SN-38 ADC, IMMU 130, IMMU-130
lampalizumab 8294 anti-factor D, FCFD4514S, RG7417
lanadelumab 9094 DX-2930, X124-G01
landogrozumab 8730 LY-2495655, LY2495655
lebrikizumab 7684 MILR1444A, RG3637, TNX-650
lenzilumab 8935 KB-003, KB003
lifastuzumab vedotin 8405 DNIB0600A, RG-7599, RG7599
ligelizumab 8997 CL-2C, NVP-QGE031, QGE031
lintuzumab 7983 ACTIMAB®, HuM195, SGN-33, SMART M195
lirilumab 9310 1-7F9, BMS-986015, IPH2102
lorvotuzumab mertansine 7431 BB-10901, IMGN901
lulizumab pegol 8460 BMS-931699, BMS931699
lutikizumab 9297 ABT-981, E26.13-SS-X3
LY2928057 8416
LY3002813 8357
LY3022855 9109 IMC-CS4
 
M Back to top
MAB92 9665
MABp1 8089 Xilonix® (proposed trade name)
margetuximab 8686 MGAH-22
mavrilimumab 7785 CAM-3001
MCS110 9110
mepolizumab 7685 Nucala®, SB-240563
milatuzumab 8267 hLL1, IMMU-115
mitumomab 7981 monoclonal antibody BEC2
MM-141 8930
MM-151 9125
mogamulizumab 6477 KW-0761, Poteligeo®
monalizumab 8323 humZ270, IPH-2201, NN8765-3658
moxetumomab pasudotox 7675 CAT-8015, GCR-8015, HA22
MOXR0916 9245 MOXR 0916, RG7888
muromonab-CD3 6889 L04AA02, OKT-3, Orthoclone Okt3®
 
N Back to top
natalizumab 6591 AN100226, anti-alpha4 integrin, anti-VLA4, Tysabri®
necitumumab 8090 11F8, IMC-11F8, LY3012211, Portrazza®
nemolizumab 8720 CIM 331, CIM331
nesvacumab 8457 REGN-910, REGN910, SAR307746
nimotuzumab 7988 h-R3, THERACIM®, Theraloc®
nivolumab 7335 BMS-936558, MDX-1106, ONO-4538, Opdivo®
 
O Back to top
obinutuzumab 6941 GA-101, GA101, Gazyva®
ocrelizumab 7580 2H7, Ocrevus®, PRO70769, RG1594
ofatumumab 6778 Arzerra®, GSK 1841157, GSK1841157, humax-CD20
olaratumab 9172 IMC-3G3, Lartruvo®, LY3012207
oleclumab 9596 MEDI 9447, MEDI-9447
omalizumab 6890 IGE25, olizumab, R03DX05, RG-3648, rhumab-E25, Xolair®
onartuzumab 8966 MetMAb, OA-5D5, OA5D5, PRO 143966
opicinumab 8923 BIIB-033, BIIB033
OPN305 9408 OPN-305, VK5A/H4
OSE-127 9604 Effi-7
otelixizumab 8458 ChAglyCD3, TRX4
ozanezumab 8254 GSK-1223249, GSK1223249
ozoralizumab 9638 ATN-103, PF-5230896
 
P Back to top
pamrevlumab 8928 FG-3019
panitumumab 6883 ABX-EGF, ABX-EGF Mab, Vectibix®
pascolizumab 7786 SB-240683
pembrolizumab 7499 Keytruda®, lambrolizumab, MK-3475
pemtumomab 8031 HMFG1, HuHMFG-1
pertuzumab 5046 2C4, Omnitarg®, Perjeta®
PF-00547659 9340 PF-547659, SHP647
pidilizumab 7692 BAT mAb, CT-011, MDV9300
plozalizumab 8921 hu1D9, MLN-1202, MLN1202
polatuzumab vedotin 8404 ACD79B-VCMMAE, RG-7596, RG7596, RO5541077-000
 
Q Back to top
quilizumab 8998 47H4 v5 hulgG1, MEMP1972A, RG-7449
 
R Back to top
racotumomab 7995 1E10, Vaxira®
ramucirumab 7390 Cyramza®, IMC-1121B
ranibizumab 6779 Fab-12 variant Y0317, Lucentis®, muMAb VEGF A.4.6.1, rhuFab V2
remtolumab 9597 A-1230717, ABT-122
reslizumab 8091 CDP-835, CDP835, Cinqair®, JES1-39D10, SCH55700
rilonacept 6790 Arcalyst®, IL-1 Trap, interleukin-1 Trap
rilotumumab 7986 AMG 102, AMG102
risankizumab 8922 ABBV-066, BI 655066, BI-655066
rituximab 6780 HSDB 7455, MabThera®, Rituxan®
romosozumab 8092 AMG-785, CDP-7851, Evenity (proposed trade name)
rontalizumab 9640 9F3v13, RhuMAB IFNalpha, rhuMAb interferon-α
rovelizumab 9598 Hu23F2G, LeukArrest
 
S Back to top
sacituzumab govitecan 8253 hRS7-SN-38-ADC, IMMU-132
sarilumab 7999 Kevzara®, REGN88, SAR153191
satralizumab 9093 SA-237, SA237, sapelizumab (perviously known as)
secukinumab 8078 AIN 457, AIN457, Cosentyx®, NVP-AIN457
seribantumab 8297 MM-121, SAR256212
sifalimumab 8257 MDX-1103, MEDI-545, MEDI545
siltuximab 7396 cLLB8, CNTO 328, Sylvant®
simtuzumab 8412 AB0024, GS 6624, GS-6624
sirukumab 7989 CNTO 136, CNTO-136, Plivensia (proposed trade name)
solanezumab 6932 LY-2062430
STM 434 8991
 
T Back to top
tabalumab 8000 LY 2127399, LY2127399
tanezumab 8415 PF-04383119, PF04383119, RN624
tarextumab 8453 OMP-59R5
tesidolumab 8711 LFG-316, LFG316
tezepelumab 8933 AMG 157, AMG-157, MEDI-9929, MEDI9929
tigatuzumab 9334 CS-1008, humanized LM1 TRA-8
tildrakizumab 8093 MK-3222, MK3222, SCH-900222, SCH900222
timolumab 9097 8c10, BTT-1023, BTT1023, r8c10, SI-3106, SI-636
tocilizumab 6881 Actemra®, R-1569, RG-1569, RHPM-1, RoActemra®
tositumomab 6781 Bexxar®, V10XA53
tralokinumab 8001 BAK1.1, CAT-354
trastuzumab 5082 D5v8, Herceptin®, R-597
trastuzumab emtansine 6928 ado-trastuzumab emtansine, Kadcyla®, PRO-132365, RG-3502
tremelimumab 8462 CP-675, CP-675,206, CP-675206, ticilimumab
trevogrumab 8929 REGN-1033, REGN1033, SAR-391786, SAR391786
 
U Back to top
ublituximab 8920 LFB-R603, TG-1101, TGTX-1101
ulocuplumab 9161 BMS-936564, MDX-1338
urelumab 9311 BMS 663513, BMS-663513
ustekinumab 6885 CNTO-1275, L04AC05, Stelara®, TT-20
utomilumab 9244 PF-05082566
 
V Back to top
vadastuximab talirine 9434 SGN-CD33A
vanucizumab 9132 RG-7221, RG7221, RO5520985
vedolizumab 7437 Entyvio®, LDP-02, LDP02, MLN-0002, MLN-002, MLN002
veltuzumab 8268 hA20, IMMU-106
vobarilizumab 8363 ALX-0061
vunakizumab 9296 SHR-1314
VX15/2503 8932 mAb 62-7
 
X Back to top
Xilonix TN 8528
 
Y Back to top
yttrium (90Y) clivatuzumab tetraxetan 8087 90Y-hPAM4, hPAM4, hPAM4-Cide, IMMU-107