The IUPHAR/BPS Guide to PHARMACOLOGY complete ligand list

Synthetic, semi-synthetic and natural peptides encoded in genomes other than human, rat and mouse (including oligopeptides and cyclic peptides).

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Ligand name ID Synonyms
A Back to top
A-71378 894 A 71378, A71378
A-71623 858 A 71623, A71623, L-phenylalaninamide
A-71915 4856 A 71915, A71915, H-3048
A8Δ71-73 5780
abaloparatide 8299 BA058, Tymlos®
abarelix 1188 Plenaxis®, PPI 149, R 3827
A(4-24)(B7-24)H2 8346 A(4-24)(B7-24)H2 relaxin
A(4-24)(B7-24)H2 chain A 8347 A(4-24)H2 relaxin
A(4-24)(B7-24)H2 chain B 8348 (B7-24)H2 relaxin
abicipar pegol 8371 AGN-150998, MP0112
ABS-201 5308 ABS 201, ABS201
ABS-212 5307 ABS 212, ABS212
Abz-Ser-Pro-Tyr(NO2)-OH 5132 o-aminobenzoyl-Ser-Pro-Tyr(NO2)-OH, TBC5182
AC-178,335 2065 AC 178335
AC187 689 AC 187, AC-187, acetyl-(Asn30,Tyr32)-calcitonin8-32, salmon calcitonin (8-32) reduced
Ac-c[Cys-Glu-His-D-Phe-Arg-Trp-D-Cys]-Pro-Pro-Lys-Asp-NH2 1342
[Ac-D-2Nal1,D4CPA2,D-3Pal3,6,Leu8, D-Ala10]GnRH-II 5583
Ac-GRP-(20-26)-methylester 625 N-acetyl-GRP-(20-26)-ethylester
[Ac-His1]PACAP-27 2263 [Ac-His1]pituitary adenylate cyclase activating polypeptide-27
[125I][Ac-His1]PACAP-27 2260 [125I]-[Ac-His1]pituitary adenylate cyclase activating polypeptide-27
Ac-hMCH-(6-16)-NH2 1290 hAc-MCH(6-16)-NH2, human Ac-MCH6-16-NH2
A(Δ10/15C)INSL3 8332
aclerastide 8300 DSC-127, DSC127, NorLeu3-A(1-7)
Ac-Lys-[MeAla6,Leu8,des-Arg9]bradykinin 651 N-acetylated-[Lys,MeAla6,Leu8,des-Arg9]bradykinin, Ac-[MeAla6,Leu8,des-Arg9]kallidin
AcPhe-Orn-Pro-D-Cha-Trp-Arg 3853 AcF[OP-D-Cha-Wr]
Ac-Phe-Trp-Ala-His(τBZL)-Nip-Gly-Arg-NH2 6191
Ac-RHYPLWR 8380
Ac-RYYRIK-NH2 1679
Ac-RYYRWK-NH2 1680
A(C10/15S)INSL3 8331
ACTH-(11-24) 1332 ACTH (11-24), adrenocorticotropic hormone (11-24)
ACTH-(1-24) 1330 ACTH (1-24), adrenocorticotropic hormone (1-24)
[125I]ACTH-(1-24) 3767 [125I]-ACTH(1-24), [125I]-adrenocorticotropin(1-24)
[Ac-Tyr1, D-Arg2]GHRH-(1-29)-NH2 (human) 1125
AF12198 4861 AF 12198, AF-12198
A(4-24)(F23A)H2 8349
afamelanotide 1324 α-NDP-MSH, [Nle4,dPhe7]α-MSH, NDP-MSH
AFT-II 2613 neurotoxin-2, Toxin AFII, Toxin AFT-II
ω-agatoxin IIIA 2528 omega-Aga-IIIA, Omega-agatoxin-Aa3a
ω-agatoxin IVA 2529 omega-Aga-IVA, Omega-agatoxin-Aa4a
ω-agatoxin IVB 2530 Omega-agatoxin-Aa4b
A(10-24)INSL3 8330
A(9-26)INSL3 8329
AL-78898A 9219 4(1MeW), POT-4
[Ala1,12,Aib3,Gln10,hArg11,Trp14,Arg19]PTH-(1-34)-NH2 5573 [Ala1,12,Aib3,Gln10,hArg11,Trp14,Arg19]-hPTH 1-34-NH2, M-PTH(1-34)
[Ala1,12,Aib3,Gln10,hArg11,Trp14,Arg19]PTH-(1-21)-NH2 (human) 5575 [Ala1,12,Aib3,Gln10,hArg11,Trp14,Arg19]hPTH-(1-21)-NH2, [Ala1,12,Aib3,Gln10,hArg11,Trp14,Arg19]-PTH 1-21-NH2 (human), M-PTH(1-21)
[Ala1,12,Aib3,Gln10,hArg11,Trp14,Arg19]PTH-(1-28)-NH2 (human) 5574 [Ala1,12,Aib3,Gln10,hArg11,Trp14,Arg19]-hPTH 1-28-NH2, [Ala1,12,Aib3,Gln10,hArg11,Trp14,Arg19]-PTH 1-28-NH2 (human), M-PTH(1-28)
[Ala1,12,Aib3,Gln10,hArg11,Trp14]PTH-(1-14)-NH2 5576 [Ala1,12,Aib3,Gln10,hArg11,Trp14]-hPTH 1-14-NH2, [Ala1,12,Aib3,Gln10,hArg11,Trp14]-PTH 1-14-NH2 (human), M-PTH(1-14)
[Ala31,Aib32]NPY 1560
[Ala31,Aib32]NPY (pig) 1522
[Ala11, D-Leu15]orexin-B 1700
[Ala6, D-Trp8]galanin-(1-15)-ol 6146
[Ala1,3,11,15]ET-1 3837 [Ala1,3,11,15]endothelin-1
[125I][Ala1,3,11,15]ET-1 3760 [125I]-[Ala1,3,11,15]endothelin-1, [125I][Ala1,3,11,15]endothelin-1
alafosfalin 9503 alaphosphin
[2Ala]-galparan 6098
β-Ala-Lys-AMCA 9501 β-alanyl-lysyl-N-7-amino-4-methylcoumarin-3-acetic acid, Beta-Ala-Lys-N(epsilon)-AMCA
[βAla8]neurokinin A-(4-10) 2112 [βAla8]neurokinin A (4-10)
alarelin 9342
[Ala11,22,28]VIP 2278 [Ala11,22,28]vasoactive intestinal peptide
albiglutide 7386 Eperzan®, GSK716155, Tanzeum®
alglucosidase alfa 7561 Lumizyme®, Myozyme®, rhGAA
alpha1-proteinase inhibitor 7487 A1AT, A1PI, alpha 1-antitrypsin, Aralast®, Prolastin®, serum trypsin inhibitor
AlprolixTM 7373
ALX40-4C 607 ALX 40-4C, N-alpha-acetyl-nona-D-arginine amide acetate
AM3 5635 DOTA-Tyr-cyclo(DAB-Arg-cyclo(Cys-Phe-D-Trp-Lys-Thr-Cys)
amanitin 4632 α-amanitin
AM-(22-52) (human) 706 AM (22-52), human adrenomedullin (22-52)
AM-(11-50) (rat) 704 AM (11-50), rat adrenomedullin (11-50)
AM-(20-50) (rat) 705 rat adrenomedullin (20-50)
[125I]AM (rat) 3768 [125I]-adrenomedullin, [125I]-AM
anakinra 6972 antril, Kineret®
analog 30 [PMID:18543899] 5647
analog 31 [PMID:18543899] 5648
analog 32 [PMID:18543899] 7763
analog 3 [PMID:18543899] 5646
anantin 4866
andexanet alfa 7576 PRT064445, PRT4445, r-antidote
[125I]angiotensin-(1-7) (human, mouse, rat) 5578 [125I]ang-(1-7)
[125I]ANP (human) 4845 [125I]-ANP
antarelix 1189 D-23234, EP 24332
antisauvagine 931 [dPhe11,His12]Svg(11-40), antisauvagine-30
[125I]antisauvagine 930
AP811 4870 AP 811, AP-811
apamin 2311
[125I]apelin-13 602
apelin-13(F13A) 5354
APETx-1 2609 Toxin APETx1
APETx2 4135
aprotinin  {Sp: Bovine} 6570 basic protease inhibitor (BPI), BPTI, pancreatic trypsin inhibitor, Trasylol®
AR305352 7043
[Arg16]chicken secretin 3293 [R16]chicken secretin
arginine vasotocin 2169 AVT, [Arg8]vasotocin
[Arg14Lys15]N/OFQ 1689 [Arg14Lys15]nociceptin, [Arg14Lys15]nociceptin/orphanin FQ, [Arg14Lys15]orphanin FQ
[Arg19]PTH-(1-34) (human) 1792 [Arg19]-PTH 1-34 (human)
ARL-15849 859 AR-R 15849, ARL 15849XX, FPL 15849
ASIP [90-132 (L89Y)] 1327 agouti-signaling protein [90-132 (L89Y)], agouti-signaling protein[90-132 (L89Y)]
astressin 925
[125I]astressin 924
[Asu7,23']β-ANP-(7-28) 4852 [Asu7,23']-β-ANP7-28
atacicept 9517 TACI-Fc, TACI-Ig
atosiban 2213 Antocin®, d[D-Tyr(Et)2,Thr4,Orn8]vasotocin, d[D-Tyr(Et)2,Thr4]OVT, ORF22164, RWJ 22164, Tractocile®
ATX-II 2614 anemonia viridis toxin 2, Sea anemone toxin II (Anemonia sulcata), toxin ATX-II
aTyr 1940 8738 ATYR1940, HRS(1-506), Resolaris
Ava3 3855
Ava5 3856
[Ava9,10,Ava14,15]-Ac-hMCH6-16-NH2 1307 compound 30 [PMID:12009900]
[3H]AVP (human, mouse, rat) 2175 [3H]arginine vasopressin
AY77 9455 compound 14 [PMID: 26819675]
AYPGKF-NH2 4061 AY-NH2
azapro-3 9221
 
B Back to top
B-10356 652
B-9430 653 B 9430, B9430
B-9858 654 B 9858, Lys-Lys-[Hyp3, Igl5, D-Igl7, Oic8]des-Arg9-BK
B-9958 655 B9958, des-Arg(9)-BK
BASS antagonist 5644 BASS antagonist Analog 4
BAY 55-9837 2269
[125I]BAY 55-9837 2281
BBL-454 895 BBL 454, BBL454
BC-254 896 BC 254, BC254
BC-264 897 BC 264, BC264
Bc-III 2615 major neurotoxin BcIII
[125I]BDNF (human) 4846 [125I]-BDNF, [125I]-brain-derived neurotrophic factor
BeKm-1 2610 neurotoxin BeKm-1, potassium channel toxin γ-KTx 2.1
BgK 2551 Potassium channel toxin Bgk
[125I]BgK (W5Y / Y26F) 2565
(B7-33)H2 9321
[125I]BH-AMY (rat, mouse) 3770 [125I]-BH-AMY, [125I]-Bolton Hunter amylin
[125I]BH-MIT1 8522
[125I]BH-NMB (human, mouse, rat) 3771 [125I]-BH-NMB, [125I]-Bolton Hunter neuromedin B
[125I]BH-[Sar9,Met(O2)11]SP 3769 [125I]-BH-[Sar9,Met(O2)11]SP, [125I]-Bolton Hunter-[Sar9,Met(O2)11]substance P
[3H]BH-[Sar9,Met(O2)11]SP 3811 [3H]-Bolton Hunter-[Sar9,Met(O2)11]substance P, [3H]-BH-[Sar9,Met(O2)11]SP
bihelical apoA-I mimetic peptide 5A 9183 5A peptide
BIM 23023 2032
BIM 23027 2033 BIM23027
BIM 23030 2034
BIM 23034 2035 DC 13-212
BIM 23050 2003 BIM-23050
BIM 23052 2004 BIM-23052, BIM23052, DC-(23-99)
BIM 23056 2036
BIM 23058 2068
BIM 23059 2037
BIM 23060 2038
BIM 23066 2039
BIM 23068 2040
BIM 23127 2162
BIM 23197 2041
BIM 23268 2083 BIM23268
BIM 23295 2069
BIM 23313 2084
BIM 23454 2026
BIM 23627 2027 H-5886, MW 1164
BIM28011 3857 [D-Ala2,Ala8,9,15,27,D-Arg29]hGHRH(1-29)NH2, BIM 28011
BIM 28163 1101 BIM-28163
[125I]BIM23027 3772 [125I]-BIM 23027, [125I]-BIM23027
BIO1211 6589 BIO 1211, BIO-1211
bivalirudin 6470 Angiomax®
[3H]BK (human, mouse, rat) 3812 [3H]-BK, [3H]-bradykinin
blisibimod 9518 A-623, AGP3 peptibody, AMG 623, Fc-Agp-3
BOC-ATE 2042
BODIPY® TMR-NMU 3858
bombesin 616
[Bpa1,Ile13]motilin (human) 1452
[Bpa6,Tyr10]secretin-27 (rat) 1154
BP-CCL3 752 BP-LD78α, BP-MIP-1α, photoactivatable macrophage inflammatory protein-1α
BPTI-K15R/R17G 7897
BQ123 997 BQ 123, BQ-123
BQ 3020 3859 BQ-3020, BQ3020
[125I]BQ3020 1005 [125I]-BQ3020
[3H]BQ123 1003 [3H]-BQ123, [3H]cyc(DTrp-DAsp-Pro-DVal-Leu
brimapitide 9101 AM-111, D-JNKI-1, XG-102
B-R13/17K H2 relaxin 4371 AT-001, B13/17K H2 relaxin
α-bungarotoxin 3964
[125I]α-bungarotoxin 3972
[3H]α-bungarotoxin 3981
buserelin 3860 buserelin acetate, HOE 766, HOE 766A, ICI 123215, Metrelef®, Suprefact®
[125I]buserelin 1167 [125I]-buserelin
Bv8 5362 Bombina variegata protein
[Bz-Phe6]U-II (human) 2159 human [Bz-Phe6] urotensin-II
 
C Back to top
C089 5779
C21 7037
C3 1291
C7 3861 galanin(1-13)spantide
C5a hexapeptide analogue 5768 Phe-Lys-Ala-dCha-Cha-dArg
[125I]C3a (human) 3773 [125I]-C3a
[125I]C5a (human) 3774 [125I]-C5a
calciseptine 4149
calcitonin (salmon) 6973 CT (salmon), Miacalcin®
cANF4-23 4892 des[Gln18,Ser19,Gly20,Leu21,Gly22]ANP4οΎ–23-NH2
cangitoxin II 7568 cangitoxin-2, cangitoxin-II, CGTX-II
[125I]cathepsin G (human) 1017 [125I]cathepsin G
CCK-58  {Sp: Dog} 862
[3H]CCK-8 (human, mouse, rat) 4765 [3H]-CCK-8
[125I]CCL11 (human) 794 [125I]eotaxin
[125I]CCL16 (human) 1275 [125I]LEC
[125I]CCL17 (human) 3652 [125I]TARC
[125I]CCL19 (human) 3655 [125I]ELC
[125I]CCL1 (human) 814 [125I]I-309, [125I]P500, [125I]TCA-3
[125I]CCL20 (human) 3654 [125I]LARC, [125I]MIP-3α
[125I]CCL21 (human) 3656 [125I]SLC
[125I]CCL25 (human) 3657 [125I]TECK
[125I]CCL27 (human) 3653 [125I]CTACK
[125I]CCL2 (human) 762 [125I]MCAF, [125I]MCP-1, [125I]monocyte chemotactic protein-1
[125I]CCL3 (human) 763 [125I]macrophage inflammatory protein-1α, [125I]MIP-1α
[125I]CCL4 (human) 799 [125I]macrophage inflammatory protein-1β, [125I]MIP-1β
[125I]CCL5 (human) 764 [125I]RANTES, [125I]regulated upon activation normal T cell expressed and secreted
[125I]CCL7 (human) 765 [125I]MCP-3, [125I]monocyte chemotactic protein-3
[125I]CCL8 (human) 766 [125I]MCP-2, [125I]monocyte chemotactic protein-2
[125I]CCL1 (mouse) 5546
CCL20-SEAP(His)6 809 LARC fused with secreted alkaline phosphatase, LARC-SEAP(His)6, MIP-3α fused with secreted alkaline phosphatase
cenderitide 9066 CD-NP
cetrorelix 1190 Cetrotide®, SB-075
[125I]cetrorelix 1186
CGEN-856 7041 P61
CGEN-857 7040 P33
CGEN-855A 6241
CGP 23996 2005 CGP-23996, CGP23996
CGP42112 3944 CGP 42112, CGP 42112A
[125I]CGP 23996 2022
[125I]CGP42112 594 [125I]-CGP42112, Cgp 42112B, Cgp-42112A
α-CGRP-(8-37) (human) 700 α-CGRP (8-37) (human), human α-calcitonin gene-related peptide (8-37)
[125I]αCGRP (human) 3766 [125I]-αcalcitonin gene-related peptide, [125I]-αCGRP
[125I]αCGRP (mouse, rat) 6567
α-CGRP-(8-37) (rat) 701 α-CGRP (8-37) (rat), rat α-calcitonin gene-related peptide (8-37)
CH 275 2006 CH-275, desAA1,2,5[D-Trp8,IAmp9]somatostatin-14
charybdotoxin 2328 ChTX
charybdotoxin-GLU32 analog 2329 ChTX-GLU32
[Cha6]U-II-(4-11) 9439
chemerin C-terminal peptide 3422 bioactive chemerin peptide, chemerin 149-157, chemerin-9
CHIPS 3724 chemotaxis inhibitory protein of S. aureus
CHIPS-(28-149) 5770 CHIPS28-149
[125I]CHIPS 1027 [125I]chemotaxis inhibitory protein of S. aureus
[(CH2NH)4,5]secretin 3755 [ψ4,5]secretin
[125I]chorionic gonadotropin (human) 3775 [125I]CG (human), [125I]-CG, [125I]-chorionic gonadotropin
C12-iE-DAP 9508
cilengitide 6597 EMD-12192, EMD-121974
4-Cl-cinnamoyl-c[DCys-4Pal-DTrp-Orn-Val-Cys]-His-amide 2161
[125I]CNP (human) 4847 [125I]-CNP
C2-NPY (pig) 1534
compound 6b [PMID: 24999562] 7927
compound 5d [PMID: 25815150] 9008
compound 8d [PMID: 24999562] 7926
compound 1 [PMID: 25241924] 7801
compound 2 [PMID: 11375253] 1292
compstatin 9218
conantokin-G 4161 conotoxin GV
concanavalin A 4162
conestat alfa 7627 rhC1INH, Ruconest®
conkunitzin-S1 toxin 7758 conk-S1, Kunitz-type conkunitzin-S1
conopeptide Y-PI1 7742
α-conotoxin ArIB 4007
α-conotoxin AuIB 3973
ω-conotoxin CVIA 2531
ω-conotoxin CVIB 2532
ω-conotoxin CVIC 2533
ω-conotoxin CVID 2534 AM-336, AM336, CNSB004, leconotide
α-conotoxin GI 3983 G1
α-conotoxin-GIC 4009
μ-conotoxin GIIIA 2630 Geographutoxin I, GTx-I, Myotoxin I
ω-conotoxin GVIA 2535
α-conotoxin ImI 3965 α-CTx ImI
α-conotoxin MI 3999
α-conotoxin MII 3970
[125I]α-conotoxin MII 3975
α-conotoxin MII [H9A, L15A] 4010
ω-conotoxin MVIIA 2536 Prialt, SNX-111, ziconotide
ω-conotoxin MVIIC 2537 ω-CTx-MVIIC, SNX-230
ω-conotoxin MVIID 2538 SNX-238
α-conotoxin PIA 3985
μ-conotoxin PIIIA 2631 μ-conotoxin P3.7
α-conotoxin PnIA 3982
α-conotoxin RgIA 4008
μ-conotoxin SmIIIA 7567
α-conotoxin TxIA 4011
contulakin-G 1575 CGX-1160
corticotropin-releasing factor  {Sp: Sheep} 913 CRF, corticoliberin, endorpholiberin
corticotropin zinc hydroxide 6967
cosyntropin 6965 Cortrosyn®
[125I][cPP(1-7), NPY(19-23), Ala31, Aib32, Gln34]hPP 3921 [125I]-[cPP(1-7), NPY(19-23), Ala31, Aib32, Gln34]hPP
[125I]CRF (ovine) 915 [125I]corticotropin
crisantaspase 7347 asparaginase, Elspar®, L-asparaginase, L-asparagine amidohydrolase
CTAP 1635
[125I]CT (human) 3776 [125I]-calcitonin (Human), [125I]-CT (Human)
CTOP 1674 Ctop-NH2, CTOPA
CTR-stimulating peptide  {Sp: Pig} 5369 calcitonin-receptor stimulating peptide, CRSP-1
CT-(8-32) (salmon) 690 CT (8-32) (salmon), salmon calcitonin (8-32)
[125I]CT (salmon) 3777 [125I]-calcitonin (Salmon), [125I]-CT (Salmon)
CXCL12-(1-17) 846 CXCL12, 1-17, SDF-1, 1-17, stromal cell-derived factor-1, N-terminal fragment
CXCL12-(1-9) 847 CXCL12, 1-9
CXCL12-(1-9) dimer 848 CXCL12, 1-9 dimer, stromal cell-derived factor-1, N-terminal fragment dimer
CXCL122 (dimer) 8535
CXCL12H25R (monomer) 8534
[125I]CXCL10 (human) 3660 [125I]IP-10
[125I]CXCL11 (human) 3661 [125I]I-TAC
[125I]CXCL12α (human) 849 [125I]SDF-1α (human), [125I]stromal cell-derived factor-1α
[125I]CXCL12β (human) 850 [125I]SDF-1β (human), [125I]stromal cell-derived factor-1β
[125I]CXCL16 (human) 3662
[125I]CXCL1 (human) 3677 [125I]GROα
[125I]CXCL5 (human) 3659 [125I]ENA-78
[125I]CXCL7 (human) 3658 [125I]NAP-2
[125I]CXCL8 (human)