Malonyl-CoA decarboxylase

Target id: 1275

Nomenclature: Malonyl-CoA decarboxylase

Abbreviated Name: MLYCD

Family: Decarboxylases

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for Malonyl-CoA decarboxylase in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - - MLYCD malonyl-CoA decarboxylase
Mouse - - Mlycd malonyl-CoA decarboxylase
Rat - - Mlycd malonyl-CoA decarboxylase
Previous and Unofficial Names
MCD | malonyl-CoA decarboxylase, mitochondrial
Database Links
BRENDA
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 4.1.1.9

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 10h [PMID: 20832306] Hs Inhibition 9.3 pIC50 1
pIC50 9.3 (IC50 5x10-10 M) [1]

References

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1. Tang H, Yan Y, Feng Z, de Jesus RK, Yang L, Levorse DA, Owens KA, Akiyama TE, Bergeron R, Castriota GA et al.. (2010) Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities. Bioorg. Med. Chem. Lett.20 (20): 6088-92. [PMID:20832306]

How to cite this page

Decarboxylases: Malonyl-CoA decarboxylase. Last modified on 16/09/2015. Accessed on 17/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1275.