CYP1A2

Target id: 1319

Nomenclature: CYP1A2

Family: CYP1 family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for CYP1A2 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - - CYP1A2 cytochrome P450 family 1 subfamily A member 2
Mouse - - Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2
Rat - - Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2
Previous and Unofficial Names
cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 | cytochrome P450 1A2 | Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d) | cytochrome P450, family 1, subfamily A, polypeptide 2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | cytochrome P450
Database Links
BRENDA
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 1.14.1.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
5H3'FPE Hs Inhibition 6.4 pIC50 1
pIC50 6.4 (IC50 4.2x10-7 M) [1]

References

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1. Liu J, Taylor SF, Dupart PS, Arnold CL, Sridhar J, Jiang Q, Wang Y, Skripnikova EV, Zhao M, Foroozesh M. (2013) Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1. J. Med. Chem.56 (10): 4082-92. [PMID:23600958]

How to cite this page

CYP1 family: CYP1A2. Last modified on 10/09/2015. Accessed on 21/09/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1319.