Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	516	15q24.1	CYP1A2	cytochrome P450 family 1 subfamily A member 2
Mouse	-	513	9 31.3 cM	Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2
Rat	-	513	8q24	Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2

Previous and Unofficial Names

cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 | cytochrome P450 1A2 | Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d) | cytochrome P450, family 1, subfamily A, polypeptide 2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | cytochrome P450

Database Links
Alphafold	P05177 (Hs), P00186 (Mm), P04799 (Rn)
BRENDA	1.14.1.1
ChEMBL Target	CHEMBL3356 (Hs), CHEMBL1671611 (Mm), CHEMBL1075125 (Rn)
Ensembl Gene	ENSG00000140505 (Hs), ENSMUSG00000032310 (Mm), ENSRNOG00000016173 (Rn)
Entrez Gene	1544 (Hs), 13077 (Mm), 24297 (Rn)
Human Protein Atlas	ENSG00000140505 (Hs)
KEGG Enzyme	1.14.1.1
KEGG Gene	hsa:1544 (Hs), mmu:13077 (Mm), rno:24297 (Rn)
Pharos	P05177 (Hs)
UniProtKB	P05177 (Hs), P00186 (Mm), P04799 (Rn)
Wikipedia	CYP1A2 (Hs)

Enzyme Reaction
EC Number: 1.14.1.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference 5H78PF Hs Inhibition 7.8 pIC50 1 ⤷ pIC50 7.8 (IC50 1.4x10-8 M) [1] 5H3'FPE Hs Inhibition 6.4 pIC50 1 ⤷ pIC50 6.4 (IC50 4.2x10-7 M) [1]