CYP2E1

Target id: 1330

Nomenclature: CYP2E1

Family: CYP2 family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for CYP2E1 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - - CYP2E1 cytochrome P450 family 2 subfamily E member 1
Mouse - - Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1
Rat - - Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1
Previous and Unofficial Names
4-nitrophenol 2-hydroxylase | cytochrome P450 2E1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | cytochrome P450, subfamily 2e1 (ethanol-inducible) | cytochrome P450, family 2, subfamily E, polypeptide 1 | cytochrome P450
Database Links
BRENDA
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 1.14.14.1

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 23 [PMID: 17125252] Hs Inhibition 7.4 pKi 1
pKi 7.4 (Ki 4x10-8 M) [1]

References

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1. Yano JK, Denton TT, Cerny MA, Zhang X, Johnson EF, Cashman JR. (2006) Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization. J. Med. Chem.49 (24): 6987-7001. [PMID:17125252]

How to cite this page

CYP2 family: CYP2E1. Last modified on 11/09/2015. Accessed on 21/09/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1330.