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CYP4 family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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CYP4 family enzymes catalyse the ω-oxidation of endogenous fatty acids and eicosanoids [4]. They have been proposed as molecular targets for the treatment of fatty acid-linked orphan diseases.

Enzymes

1348
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CYP4A11 C Show summary »

CYP4A22 C Show summary »

CYP4B1 C Show summary »

CYP4F2 C Show summary »

CYP4F3 C Show summary »

CYP4F8 C Show summary »

CYP4F11 C Show summary »

CYP4F12 C Show summary »


Target Id 1348
Nomenclature CYP4F12
Previous and unofficial names cytochrome P450, subfamily IVF, polypeptide 12 | cytochrome P450, family 4, subfamily F, polypeptide 12
Genes CYP4F12 (Hs)
Ensembl ID ENSG00000186204 (Hs)
UniProtKB AC Q9HCS2 (Hs)
EC number
1.14.14.1
Inhibitors
HET0016 pIC50 7.9 [23]
Comment AC004597.1 (ENSG00000225607) is described as being highly similar to CYP4F12

CYP4F22 C Show summary »

CYP4V2 C Show summary »

CYP4X1 C Show summary »

CYP4Z1 C Show summary »

References

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.