<i>MAS1L</i> | Class A Orphans | IUPHAR/BPS Guide to PHARMACOLOGY

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MAS1L

Target not currently curated in GtoImmuPdb

Target id: 151

Nomenclature: MAS1L

Family: Class A Orphans

Annotation status:  image of a green circle Annotated and expert reviewed. Please contact us if you can help with updates.  » Email us

Gene and Protein Information
class A G protein-coupled receptor
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 378 6p22.1 MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
Previous and Unofficial Names
MAS-L | MAS-R | MRG
Database Links
Specialist databases
GPCRDB mas1l_human (Hs)
Other databases
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Agonist Comments
It has been reported that MAS1L responds to stimulation by angiotensin metabolites [1].
Biologically Significant Variants
Type:  Naturally occurring SNP
Species:  Human
Amino acid change:  D288E
Comment on frequency:  Low frequency (<10% in all tested populations)
SNP accession: 

References

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1. Gembardt F, Grajewski S, Vahl M, Schultheiss HP, Walther T. (2008) Angiotensin metabolites can stimulate receptors of the Mas-related genes family. Mol. Cell. Biochem., 319 (1-2): 115-23. [PMID:18636314]

Contributors

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How to cite this page

Stephen P.H. Alexander, Jim Battey, Helen E. Benson, Richard V. Benya, Tom I. Bonner, Anthony P. Davenport, Satoru Eguchi, Anthony Harmar, Nick Holliday, Robert T. Jensen, Sadashiva Karnik, Evi Kostenis, Wen Chiy Liew, Amy E. Monaghan, Chido Mpamhanga, Richard Neubig, Adam J. Pawson, Jean-Philippe Pin, Joanna L. Sharman, Michael Spedding, Eliot Spindel, Leigh Stoddart, Laura Storjohann, Walter (Wally) Thomas, Kalyan Tirupula, Patrick Vanderheyden.
Class A Orphans: MAS1L. Last modified on 16/06/2015. Accessed on 24/04/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=151.