protein kinase AMP-activated non-catalytic subunit beta 1 | AMPK subfamily | IUPHAR/BPS Guide to PHARMACOLOGY

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protein kinase AMP-activated non-catalytic subunit beta 1

Target not currently curated in GtoImmuPdb

Target id: 1543

Nomenclature: protein kinase AMP-activated non-catalytic subunit beta 1

Abbreviated Name: AMPKB1

Family: AMPK subfamily

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 270 12q24.1-q24.3 PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1
Mouse - 270 5F,5 Prkab1 protein kinase
Rat - 270 12q16 Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1
Previous and Unofficial Names
AMPK beta 1 | 5'-AMP-activated protein kinase 40 kDa subunit | AMPKb | protein kinase, AMP-activated, beta 1 non-catalytic subunit | protein kinase
Database Links
CATH/Gene3D
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia

Download all structure-activity data for this target as a CSV file

Activators
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Parameter Reference
MT47-100 Hs Activation 5.4 pKi 1
pKi 5.4 (Ki 3.7x10-6 M) [1]

References

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1. Scott JW, Galic S, Graham KL, Foitzik R, Ling NX, Dite TA, Issa SM, Langendorf CG, Weng QP, Thomas HE et al.. (2015) Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release. Chem. Biol., 22 (6): 705-11. [PMID:26091167]

How to cite this page

AMPK subfamily: protein kinase AMP-activated non-catalytic subunit beta 1. Last modified on 30/03/2016. Accessed on 20/02/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1543.