Cathepsin A

Nomenclature: Cathepsin A

Family: S10: Carboxypeptidase Y

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 480 20q13.12 CTSA cathepsin A
Mouse - 474 2 H3 Ctsa cathepsin A
Rat - 456 3q42 Ctsa cathepsin A
Previous and Unofficial Names
GSL
PPGB
carboxypeptidase C
protective protein for beta-galactosidase (galactosialidosis)
lysosomal protective protein
carboxypeptidase-L
carboxypeptidase Y-like kininase
deamidase
lysosomal carboxypeptidase A
urinary kininase
cathepsin A
protective protein for beta-galactosidase
PPCA
Database Links
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
ExplorEnz
GeneCards
GenitoUrinary Development Molecular Anatomy Project
Human Protein Reference Database
InterPro
KEGG BRITE Hierarchy
KEGG Gene
MEROPS
OMIM
Orphanet Gene
PhosphoSitePlus
RefSeq Nucleotide
RefSeq Protein
TreeFam
UniGene Hs.
UniProtKB
Enzyme Reaction
EC Number: 3.4.16.5
Clinically-Relevant Mutations and Pathophysiology
Disease:  Galactosialidosis
OMIM:  256540
Orphanet:  351
References: 
Mutations not determined

The Guide to PHARMACOLOGY curates quantitative bioactivity mappings for all approved, clinical and selected actively pursued research targets. Data for additional protein mappings from medicinal chemistry papers and selected PubChem Bioassays can be found in the ChEMBL links.

How to cite this page

S10: Carboxypeptidase Y: Cathepsin A. Last modified on 11/03/2014. Accessed on 01/09/2014. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1581.