Dipeptidyl-peptidase 7

Target id: 1605

Nomenclature: Dipeptidyl-peptidase 7

Family: S28: Lysosomal Pro-Xaa carboxypeptidase

Annotation status:  image of an orange circle Annotated and awaiting review. Please contact us if you can help with reviewing.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for Dipeptidyl-peptidase 7 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 492 9q34.3 DPP7 dipeptidyl peptidase 7
Mouse - 506 2 A3 Dpp7 dipeptidylpeptidase 7
Rat - 500 3p13 Dpp7 dipeptidylpeptidase 7
Previous and Unofficial Names
DPPII | dipeptidyl aminopeptidase II | dipeptidyl peptidase 2 | dipeptidyl peptidase II | Dpp2 | quiescent cell proline dipeptidase | QPP | dipeptidyl-peptidase 7
Database Links
Specialist databases
MEROPS S28.002 (Hs)
Other databases
BRENDA
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.4.14.2

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
UAMC00039 Hs Inhibition 10.1 pKi 1
pKi 10.1 (Ki 8.2x10-11 M) [1]

References

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1. Maes MB, Martinet W, Schrijvers DM, Van der Veken P, De Meyer GR, Augustyns K, Lambeir AM, Scharpé S, De Meester I. (2006) Dipeptidyl peptidase II and leukocyte cell death. Biochem. Pharmacol.72 (1): 70-9. [PMID:16725115]

How to cite this page

S28: Lysosomal Pro-Xaa carboxypeptidase: Dipeptidyl-peptidase 7. Last modified on 21/11/2013. Accessed on 12/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1605.