Caspase 14

Target id: 1627

Nomenclature: Caspase 14

Family: C14: Caspase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for Caspase 14 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 242 19p13.1 CASP14 caspase 14
Mouse - 257 10 C1 Casp14 caspase 14
Rat - 246 7q11 Casp14 caspase 14
Previous and Unofficial Names
mini-ICE | MICE | caspase 14, apoptosis-related cysteine peptidase
Database Links
Specialist databases
MEROPS C14.018 (Hs)
Other databases
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.4.22.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
grassystatin A Hs Inhibition 5.3 pIC50 1
pIC50 5.3 (IC50 5x10-6 M) [1]

References

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1. Kwan JC, Eksioglu EA, Liu C, Paul VJ, Luesch H. (2009) Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation. J. Med. Chem.52 (18): 5732-47. [PMID:19715320]

How to cite this page

C14: Caspase: Caspase 14. Last modified on 29/07/2015. Accessed on 19/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1627.