MMP11

Target id: 1635

Nomenclature: MMP11

Family: M10: Matrix metallopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for MMP11 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 488 22q11.23 MMP11 matrix metallopeptidase 11
Mouse - 492 10 C1 Mmp11 matrix metallopeptidase 11
Rat - 491 20p12 Mmp11 matrix metallopeptidase 11
Previous and Unofficial Names
SL-3 | ST3 | STMY3 | matrix metallopeptidase 11 (stromelysin 3)
Database Links
Specialist databases
MEROPS M10.007 (Hs)
Other databases
BRENDA
CATH/Gene3D
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 10 [PMID: 18790648] Hs Inhibition 6.6 pKi 1
pKi 6.6 (Ki 2.3x10-7 M) [1]

References

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1. Georgiadis D, Yiotakis A. (2008) Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. Bioorg. Med. Chem.16 (19): 8781-94. [PMID:18790648]

How to cite this page

M10: Matrix metallopeptidase: MMP11. Last modified on 28/07/2015. Accessed on 15/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1635.