MMP11

Target id: 1635

Nomenclature: MMP11

Family: M10: Matrix metallopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for MMP11 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 488 22q11.23 MMP11 matrix metallopeptidase 11
Mouse - 492 10 C1 Mmp11 matrix metallopeptidase 11
Rat - 491 20p12 Mmp11 matrix metallopeptidase 11
Previous and Unofficial Names
SL-3 | ST3 | STMY3 | matrix metallopeptidase 11 (stromelysin 3)
Database Links
Specialist databases
MEROPS M10.007 (Hs)
Other databases
BRENDA
CATH/Gene3D
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 10 [PMID: 18790648] Hs Inhibition 6.6 pKi 1
pKi 6.6 (Ki 2.3x10-7 M) [1]

References

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1. Georgiadis D, Yiotakis A. (2008) Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. Bioorg. Med. Chem., 16 (19): 8781-94. [PMID:18790648]

How to cite this page

M10: Matrix metallopeptidase: MMP11. Last modified on 28/07/2015. Accessed on 22/07/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1635.