MMP25

Target id: 1647

Nomenclature: MMP25

Family: M10: Matrix metallopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for MMP25 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 562 16p13.3 MMP25 matrix metallopeptidase 25
Mouse - 615 17 A3.3 Mmp25 matrix metallopeptidase 25
Rat - - 10q12 Mmp25 matrix metallopeptidase 25
Previous and Unofficial Names
leukolysin | MT6-MMP | MMP20 | MMPL1
Database Links
Specialist databases
MEROPS M10.024 (Hs)
Other databases
BRENDA
CATH/Gene3D
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
CGS-27023A Hs Inhibition 8.8 pIC50 1
pIC50 8.8 (IC50 1.5x10-9 M) [1]

References

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1. Nuti E, Casalini F, Santamaria S, Gabelloni P, Bendinelli S, Da Pozzo E, Costa B, Marinelli L, La Pietra V, Novellino E et al.. (2011) Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors. Eur J Med Chem, 46 (7): 2617-29. [PMID:21514700]

How to cite this page

M10: Matrix metallopeptidase: MMP25. Last modified on 16/03/2017. Accessed on 23/07/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1647.