Quaternary Structure: Complexes

Interferon-α/β receptor

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	515	21q22.11	IFNAR2	interferon alpha and beta receptor subunit 2
Mouse	1	513	16 52.82 cM	Ifnar2	interferon (alpha and beta) receptor 2

Previous and Unofficial Names

IFNABR | interferon (alpha, beta and omega) receptor 2

Database Links
Alphafold	P48551 (Hs), O35664 (Mm)
CATH/Gene3D	2.60.40.10
ChEMBL Target	CHEMBL2364170 (Hs)
DrugBank Target	P48551 (Hs)
Ensembl Gene	ENSG00000159110 (Hs), ENSMUSG00000022971 (Mm)
Entrez Gene	3455 (Hs), 15976 (Mm)
Human Protein Atlas	ENSG00000159110 (Hs)
KEGG Gene	hsa:3455 (Hs), mmu:15976 (Mm)
OMIM	602376 (Hs)
Pharos	P48551 (Hs)
UniProtKB	P48551 (Hs), O35664 (Mm)
Wikipedia	IFNAR2 (Hs)

Immunopharmacology Comments

A subunit of the functional receptor for various interferons (NOT interferon γ).

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  Immune regulation

Immuno Process:  Cytokine production & signalling