Interferon α/β receptor 2 | Interferon receptor family | IUPHAR/BPS Guide to PHARMACOLOGY

Interferon α/β receptor 2

Target id: 1724

Nomenclature: Interferon α/β receptor 2

Family: Interferon receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interferon α/β receptor 2 has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interferon-α/β receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 515 21q22.11 IFNAR2 interferon alpha and beta receptor subunit 2
Mouse 1 513 Ifnar2 interferon (alpha and beta) receptor 2
Previous and Unofficial Names
IFNABR | interferon (alpha, beta and omega) receptor 2
Database Links
CATH/Gene3D
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
A subunit of the functional receptor for various interferons (NOT interferon γ).
Immuno Process Associations
Immuno Process:  Inflammation
GO Annotations:  Associated to 3 GO processes
GO:0004905 type I interferon receptor activity IDA
GO:0060337 type I interferon signaling pathway IDA
GO:0060338 regulation of type I interferon-mediated signaling pathway TAS
Immuno Process:  Immune regulation
GO Annotations:  Associated to 1 GO processes
GO:0060338 regulation of type I interferon-mediated signaling pathway TAS
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 5 GO processes
GO:0004905 type I interferon receptor activity IDA
GO:0035455 response to interferon-alpha IDA
GO:0035456 response to interferon-beta IMP
GO:0060337 type I interferon signaling pathway IDA
GO:0060338 regulation of type I interferon-mediated signaling pathway TAS

How to cite this page

Interferon receptor family: Interferon α/β receptor 2. Last modified on 10/04/2017. Accessed on 22/09/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1724.