Interferon α/β receptor 2

Target id: 1724

Nomenclature: Interferon α/β receptor 2

Family: Interferon receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interferon α/β receptor 2 has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interferon-α/β receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 515 21q22.11 IFNAR2 interferon alpha and beta receptor subunit 2
Mouse 1 513 Ifnar2 interferon (alpha and beta) receptor 2
Previous and Unofficial Names
IFNABR | interferon (alpha, beta and omega) receptor 2
Database Links
CATH/Gene3D
DrugBank Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
A subunit of the functional receptor for various interferons (NOT interferon γ).
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process ID:  2
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  type I interferon receptor activity (GO:0004905) IDA
type I interferon signaling pathway (GO:0060337) IDA
regulation of type I interferon-mediated signaling pathway (GO:0060338) TAS
References: 
Immuno Process:  Immune regulation
Immuno Process ID:  6
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  regulation of type I interferon-mediated signaling pathway (GO:0060338) TAS
References: 
Immuno Process:  Cytokine production & signalling
Immuno Process ID:  9
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  type I interferon receptor activity (GO:0004905) IDA
response to interferon-alpha (GO:0035455) IDA
response to interferon-beta (GO:0035456) IMP
type I interferon signaling pathway (GO:0060337) IDA
regulation of type I interferon-mediated signaling pathway (GO:0060338) TAS
References: 

How to cite this page

Interferon receptor family: Interferon α/β receptor 2. Last modified on 10/04/2017. Accessed on 12/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1724.