Interleukin 10 receptor, β subunit

Target id: 1728

Nomenclature: Interleukin 10 receptor, β subunit

Family: IL-10 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interleukin 10 receptor, β subunit has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interleukin-10 receptor
Interleukin-22α1/10β heteromer
Interferon-λ receptor 1
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 325 21q22.11 IL10RB interleukin 10 receptor subunit beta
Mouse 1 349 Il10rb interleukin 10 receptor, beta
Rat - - Il10rb interleukin 10 receptor subunit beta
Previous and Unofficial Names
CRF2-4 | CRFB4 | IL-10R2 | Il10rb | Interleukin-10 β | interleukin 10 receptor, beta
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
Interleukin 10 receptor, β subunit is a component of the functional receptor heterodimers for interleukins 10 and 22 and for interferons λ1, λ2 and λ3.
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process ID:  2
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  inflammatory response (GO:0006954) TAS
References: 
Immuno Process:  Cytokine production & signalling
Immuno Process ID:  9
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  cytokine-mediated signaling pathway (GO:0019221) IEA
References: 

How to cite this page

IL-10 receptor family: Interleukin 10 receptor, β subunit. Last modified on 06/04/2017. Accessed on 17/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1728.