Interleukin 20 receptor, β subunit

Target id: 1730

Nomenclature: Interleukin 20 receptor, β subunit

Family: IL-10 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interleukin 20 receptor, β subunit has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interleukin-20 receptor
Interleukin-22α1/20β heteromer
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 311 03q22.3 IL20RB interleukin 20 receptor subunit beta
Mouse - - Il20rb interleukin 20 receptor beta
Rat - - Il20rb interleukin 20 receptor subunit beta
Previous and Unofficial Names
DIRS1 | FNDC6 | IL-20R2 | fibronectin type III domain containing 6 | interleukin 20 receptor beta
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
Interleukin 20 receptor, β subunit is a component of the functional receptor heterodimers for interleukins 19, 20 and 24.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
Immuno Process ID:  9
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  interleukin-10 receptor activity (GO:0004920) IBA
negative regulation of interferon-gamma production (GO:0032689) IEA
negative regulation of interleukin-2 production (GO:0032703) IEA
positive regulation of interleukin-10 production (GO:0032733) IEA
positive regulation of interleukin-4 production (GO:0032753) IEA
References: 
Immuno Process:  Inflammation
Immuno Process ID:  2
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  negative regulation of type IV hypersensitivity (GO:0001808) IEA
inflammatory response to antigenic stimulus (GO:0002437) IEA
References: 
Immuno Process:  T cell (activation)
Immuno Process ID:  4
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  negative regulation of type IV hypersensitivity (GO:0001808) IEA
negative regulation of T cell proliferation (GO:0042130) IEA
References: 
Immuno Process:  B cell (activation)
Immuno Process ID:  5
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  negative regulation of type IV hypersensitivity (GO:0001808) IEA
References: 
Immuno Process:  Immune regulation
Immuno Process ID:  6
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  negative regulation of type IV hypersensitivity (GO:0001808) IEA
immune response-inhibiting signal transduction (GO:0002765) IEA
negative regulation of T cell proliferation (GO:0042130) IEA
References: 
Immuno Process:  Chemotaxis & migration
Immuno Process ID:  10
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  negative regulation of T cell proliferation (GO:0042130) IEA
References: 
Immuno Process:  Cellular signalling
Immuno Process ID:  11
Comment: 
GO Annotation:  Associated to GO processes, IEA only
GO Processes:  immune response-inhibiting signal transduction (GO:0002765) IEA
negative regulation of T cell proliferation (GO:0042130) IEA
References: 

How to cite this page

IL-10 receptor family: Interleukin 20 receptor, β subunit. Last modified on 06/04/2017. Accessed on 23/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1730.