Interleukin 20 receptor, β subunit | IL-10 receptor family | IUPHAR/BPS Guide to PHARMACOLOGY

Interleukin 20 receptor, β subunit

Target id: 1730

Nomenclature: Interleukin 20 receptor, β subunit

Family: IL-10 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interleukin 20 receptor, β subunit has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interleukin-20 receptor
Interleukin-22α1/20β heteromer
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 311 03q22.3 IL20RB interleukin 20 receptor subunit beta
Mouse - - Il20rb interleukin 20 receptor beta
Rat - - Il20rb interleukin 20 receptor subunit beta
Previous and Unofficial Names
DIRS1 | FNDC6 | IL-20R2 | fibronectin type III domain containing 6 | interleukin 20 receptor beta
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
Interleukin 20 receptor, β subunit is a component of the functional receptor heterodimers for interleukins 19, 20 and 24.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 5 GO processes
GO:0004920 interleukin-10 receptor activity IBA
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GO:0032689 negative regulation of interferon-gamma production IEA
GO:0032703 negative regulation of interleukin-2 production IEA
GO:0032733 positive regulation of interleukin-10 production IEA
GO:0032753 positive regulation of interleukin-4 production IEA
Immuno Process:  Inflammation
GO Annotations:  Associated to 2 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0001808 negative regulation of type IV hypersensitivity IEA
GO:0002437 inflammatory response to antigenic stimulus IEA
Immuno Process:  T cell (activation)
GO Annotations:  Associated to 2 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0001808 negative regulation of type IV hypersensitivity IEA
GO:0042130 negative regulation of T cell proliferation IEA
Immuno Process:  B cell (activation)
GO Annotations:  Associated to 1 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0001808 negative regulation of type IV hypersensitivity IEA
Immuno Process:  Immune regulation
GO Annotations:  Associated to 3 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0001808 negative regulation of type IV hypersensitivity IEA
GO:0002765 immune response-inhibiting signal transduction IEA
GO:0042130 negative regulation of T cell proliferation IEA
Immuno Process:  Chemotaxis & migration
GO Annotations:  Associated to 1 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0042130 negative regulation of T cell proliferation IEA
Immuno Process:  Cellular signalling
GO Annotations:  Associated to 2 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0002765 immune response-inhibiting signal transduction IEA
GO:0042130 negative regulation of T cell proliferation IEA

How to cite this page

IL-10 receptor family: Interleukin 20 receptor, β subunit. Last modified on 06/04/2017. Accessed on 26/09/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1730.