Interferon-λ receptor subunit 1

Target id: 1733

Nomenclature: Interferon-λ receptor subunit 1

Family: IL-10 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interferon-λ receptor subunit 1 has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interferon-λ receptor 1
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 520 01p36.11 IFNLR1 interferon lambda receptor 1
Mouse 1 535 Ifnlr1 interferon lambda receptor 1
Rat - - Ifnlr1 interferon, lambda receptor 1
Previous and Unofficial Names
CRF2/12 | IL-28R1 | interleukin 28 receptor alpha | interferon, lambda receptor 1 | interferon
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
Interferon-λ receptor subunit 1 is the ligand binding component of the functional heterodimeric receptor for interferons λ1, λ2 and λ3
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process ID:  2
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  response to type III interferon (GO:0034342) ISS
References: 
Immuno Process:  Immune regulation
Immuno Process ID:  6
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  regulation of defense response to virus by host (GO:0050691) IDA
References: 
Immuno Process:  Cytokine production & signalling
Immuno Process ID:  9
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  cytokine receptor activity (GO:0004896) IBA
cytokine-mediated signaling pathway (GO:0019221) IBA
response to type III interferon (GO:0034342) ISS
References: 

How to cite this page

IL-10 receptor family: Interferon-λ receptor subunit 1. Last modified on 06/04/2017. Accessed on 18/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1733.