Interferon-λ receptor subunit 1

Target id: 1733

Nomenclature: Interferon-λ receptor subunit 1

Family: IL-10 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interferon-λ receptor subunit 1 has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interferon-λ receptor 1
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 520 01p36.11 IFNLR1 interferon lambda receptor 1
Mouse 1 535 Ifnlr1 interferon lambda receptor 1
Rat - - Ifnlr1 interferon, lambda receptor 1
Previous and Unofficial Names
CRF2/12 | IL-28R1 | interleukin 28 receptor alpha | interferon, lambda receptor 1 | interferon
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Immunopharmacology Comments
Interferon-λ receptor subunit 1 is the ligand binding component of the functional heterodimeric receptor for interferons λ1, λ2 and λ3
Immuno Process Associations
Immuno Process:  Inflammation
GO Annotations:  Associated to 1 GO processes
GO:0034342 response to type III interferon ISS
Immuno Process:  Immune regulation
GO Annotations:  Associated to 1 GO processes
GO:0050691 regulation of defense response to virus by host IDA
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 3 GO processes
GO:0004896 cytokine receptor activity IBA
GO:0019221 cytokine-mediated signaling pathway IBA
GO:0034342 response to type III interferon ISS

How to cite this page

IL-10 receptor family: Interferon-λ receptor subunit 1. Last modified on 06/04/2017. Accessed on 21/06/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1733.