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target has curated data in GtoImmuPdb
Target id: 2321
Nomenclature: Interleukin-1 receptor, type II
| Quaternary Structure: Subunits |
| Interleukin 1 receptor, type II (Ligand-binding subunit) |
| IL-1 receptor accessory protein (Other subunit) |
| Immunopharmacology Comments |
| Interleukin-1 receptor, type II (IL-1RII) is a heterodimer containing the ligand binding interleukin 1 receptor, type II (IL1R2) subunit and the IL-1 receptor accessory protein (IL1RAP). Unlike IL-1RI, IL-1RII is unable to transduce a signal in response to ligand binding, acting instead as a decoy receptor for its ligands IL-1α, IL-1β. |
Immunoglobulin-like family of IL-1 receptors: Interleukin-1 receptor, type II. Last modified on 21/03/2017. Accessed on 16/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2321.
