fatty acid binding protein 3

Target id: 2533

Nomenclature: fatty acid binding protein 3

Family: Fatty acid-binding proteins

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for fatty acid binding protein 3 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 133 1p33-p32 FABP3 fatty acid binding protein 3
Mouse - 133 4 D2.2 Fabp3 fatty acid binding protein 3, muscle and heart
Rat - 133 5q36 Fabp3 fatty acid binding protein 3
Previous and Unofficial Names
FABP11 | Fabph1 | Fabph4 | fatty acid binding protein 11 | H-FABP | MDGI | mammary-derived growth inhibitor
Database Links
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
RefSeq Nucleotide
RefSeq Protein
Rank order of potency (Human)
stearic acid, oleic acid, palmitic acid > linoleic acid, α-linolenic acid, arachidonic acid  [1]

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 13 [PMID: 17502136] Hs Inhibition 8.4 pKi 2
pKi 8.4 (Ki 4x10-9 M) [2]


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1. Richieri GV, Ogata RT, Kleinfeld AM. (1994) Equilibrium constants for the binding of fatty acids with fatty acid-binding proteins from adipocyte, intestine, heart, and liver measured with the fluorescent probe ADIFAB. J. Biol. Chem.269 (39): 23918-30. [PMID:7929039]

2. Sulsky R, Magnin DR, Huang Y, Simpkins L, Taunk P, Patel M, Zhu Y, Stouch TR, Bassolino-Klimas D, Parker R et al.. (2007) Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP). Bioorg. Med. Chem. Lett.17 (12): 3511-5. [PMID:17502136]

How to cite this page

Fatty acid-binding proteins: fatty acid binding protein 3. Last modified on 29/01/2016. Accessed on 25/03/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2533.