pancreatic lipase | Hydrolases | IUPHAR/BPS Guide to PHARMACOLOGY

pancreatic lipase

Target id: 2590

Nomenclature: pancreatic lipase

Abbreviated Name: PNLIP

Family: Hydrolases

Annotation status:  image of an orange circle Annotated and awaiting review. Please contact us if you can help with reviewing.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for pancreatic lipase in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 465 10q26.1 PNLIP pancreatic lipase
Mouse - 465 19 D2 Pnlip pancreatic lipase
Rat - 465 1q55 Pnlip pancreatic lipase
Previous and Unofficial Names
pancreatic triacylglycerol lipase | pancreatic triglyceride lipase | PANLI | PL
Database Links
BRENDA
CATH/Gene3D
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.1.1.3

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
orlistat Hs Inhibition 8.9 pIC50 1
pIC50 8.9 (IC50 1.3x10-9 M) [1]

References

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1. Bustanji Y, Issa A, Mohammed M, Hudaib M, Tawah, K, Alkhatib H, Almarsi I, Al-Khalidi B. (2010) Inhibition of hormone sensitive lipase and pancreatic lipase by Rosmarinus officinalis extract and selected phenolic constituents. Journal of Medicinal Plants Research, 4 (21): 2235-2242.

How to cite this page

Hydrolases: pancreatic lipase. Last modified on 12/12/2013. Accessed on 15/11/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2590.