<i>GPRC5D</i> | Class C Orphans | IUPHAR/BPS Guide to PHARMACOLOGY

GPRC5D

Target id: 261

Nomenclature: GPRC5D

Family: Class C Orphans

Annotation status:  image of a green circle Annotated and expert reviewed. Please contact us if you can help with updates.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for GPRC5D in GtoImmuPdb

Gene and Protein Information
class C G protein-coupled receptor
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 300 12p13.3 GPRC5D G protein-coupled receptor class C group 5 member D 1
Mouse 7 345 6 G1 Gprc5d G protein-coupled receptor, family C, group 5, member D 1
Rat 7 332 4q43 Gprc5d G protein-coupled receptor, class C, group 5, member D
Previous and Unofficial Names
RAIG4 | G protein-coupled receptor, class C, group 5, member D | G protein-coupled receptor
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Tissue Distribution
High expression in adult pancreas.
Medium expression in adult kidney, small intestine, spleen and testis.
Low in lung, colon, leukocyte, prostate and thymus and not detectable in brain, heart, liver, placenta, skeletal muscle and ovary.
Species:  Human
Technique:  RT-PCR
References:  1
Expression Datasets

Show »

Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website]

There should be a chart of expression data here, you may need to enable JavaScript!
General Comments
Orphan receptor.
Although it shares similarities with the retinoic acid induced genes, there is actually no evidence this gene is induced by retinoic acid.

References

Show »

1. Bräuner-Osborne H, Jensen AA, Sheppard PO, Brodin B, Krogsgaard-Larsen P, O'Hara P. (2001) Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D. Biochim Biophys Acta., 1518: 237-248. [PMID:11311935]

Contributors

Show »

How to cite this page

Hans Bräuner-Osborne.
Class C Orphans: GPRC5D. Last modified on 15/08/2014. Accessed on 15/11/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=261.