tumor associated calcium signal transducer 2

Target id: 2837

Nomenclature: tumor associated calcium signal transducer 2

Family: Tumour-associated proteins

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for tumor associated calcium signal transducer 2 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 323 1p32 TACSTD2 tumor associated calcium signal transducer 2
Mouse - 317 6 C1 Tacstd2 tumor-associated calcium signal transducer 2
Rat - 317 4q31 Tacstd2 tumor-associated calcium signal transducer 2
Previous and Unofficial Names
M1S1 | EGP-1 | TROP2 | TROP-2 | GA733-1 | RS7 antigen [2] | tumor-associated calcium signal transducer 2
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia

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Antibodies
Key to terms and symbols Click column headers to sort
Antibody Sp. Action Affinity Units Reference
sacituzumab govitecan Hs Binding - - 1
[1]
Clinically-Relevant Mutations and Pathophysiology
Disease:  Corneal dystrophy, gelatinous drop-like; GDLD
Synonyms: Gelatinous drop-like corneal dystrophy [Orphanet: ORPHA98957]
OMIM: 204870
Orphanet: ORPHA98957
Disease:  Honey-droplet corneal dystrophy
Orphanet: ORPHA98958

References

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1. Govindan SV, Qu Z, Hansen HJ, Goldenberg DM. (2013) RS7 antibodies. Patent number: US8574575. Assignee: Immunomedics, Inc.. Priority date: 01/03/2002. Publication date: 05/11/2013.

2. Stein R, Basu A, Goldenberg DM, Lloyd KO, Mattes MJ. (1994) Characterization of cluster 13: the epithelial/carcinoma antigen recognized by MAb RS7. Int. J. Cancer Suppl.8: 98-102. [PMID:8194903]

How to cite this page

Tumour-associated proteins: tumor associated calcium signal transducer 2. Last modified on 21/03/2017. Accessed on 18/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2837.