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Target not currently curated in GtoImmuPdb
Target id: 2875
Nomenclature: protein phosphatase methylesterase 1
Family: 3.1.1.- Carboxylic Ester Hydrolases, S33: Prolyl aminopeptidase
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | - | 386 | 11q13.4 | PPME1 | protein phosphatase methylesterase 1 | |
| Mouse | - | 386 | 7 E2 | Ppme1 | protein phosphatase methylesterase 1 | |
| Rat | - | 386 | 1q32 | Ppme1 | protein phosphatase methylesterase 1 | |
| Previous and Unofficial Names |
| PME-1 | PME1 |
| Database Links |
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| Alphafold | Q9Y570 (Hs), Q8BVQ5 (Mm), Q4FZT2 (Rn) |
| BRENDA | 3.1.1.89 |
| CATH/Gene3D | 3.40.50.1820 |
| ChEMBL Target | CHEMBL1293320 (Hs), CHEMBL2189138 (Mm) |
| Ensembl Gene | ENSG00000214517 (Hs), ENSMUSG00000030718 (Mm), ENSRNOG00000017227 (Rn) |
| Entrez Gene | 51400 (Hs), 72590 (Mm), 361613 (Rn) |
| Human Protein Atlas | ENSG00000214517 (Hs) |
| KEGG Enzyme | 3.1.1.89 |
| KEGG Gene | hsa:51400 (Hs), mmu:72590 (Mm), rno:361613 (Rn) |
| OMIM | 611117 (Hs) |
| Pharos | Q9Y570 (Hs) |
| RefSeq Nucleotide | NM_001271593 (Hs), NM_028292 (Mm), NM_001191838 (Rn) |
| RefSeq Protein | NP_001258522 (Hs), NP_082568 (Mm), NP_001178767 (Rn) |
| UniProtKB | Q9Y570 (Hs), Q8BVQ5 (Mm), Q4FZT2 (Rn) |
| Wikipedia | PPME1 (Hs) |
| Enzyme Reaction |
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Download all structure-activity data for this target as a CSV file 
| Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||
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