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SLC57 NiPA-like magnesium transporter family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

3033
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NIPA magnesium transporter 1 / SLC57A1 C Show summary »

Target Id 3033
Nomenclature NIPA magnesium transporter 1
Systematic nomenclature SLC57A1
Previous and unofficial names NIPA3 [2] | non imprinted in Prader-Willi/Angelman syndrome 1 | SPG6
Genes NIPA1 (Hs), Nipa1 (Mm), Nipa1 (Rn)
Ensembl ID ENSG00000170113 (Hs), ENSMUSG00000047037 (Mm), ENSRNOG00000042702 (Rn)
UniProtKB AC Q7RTP0 (Hs), Q8BHK1 (Mm)
RESOLUTE NIPA1 (Hs)
Substrates
Mg2+ [1]
Sr2+, Fe2+ and Co2+ to a lesser extent [2]
Comment Human tissue expression: Constitutively expressed at low levels, with significant enrichment in the brain [3].
Mouse tissue expression: Widely expressed, including in the heart, kidney, liver, colon, less in the brain, and not in the small intestine [1].

NIPA magnesium transporter 2 / SLC57A2 C Show summary »

NIPA like domain containing 1 / SLC57A3 C Show summary »

NIPA like domain containing 2 / SLC57A4 Show summary »

NIPA like domain containing 3 / SLC57A5 C Show summary »

NIPA like domain containing 4 / SLC57A6 Show summary »

Further reading

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References

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How to cite this family page

Database page citation:

SLC57 NiPA-like magnesium transporter family. Accessed on 22/06/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1009.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.