SLC60 Glucose transporters | Transporters | IUPHAR/BPS Guide to PHARMACOLOGY

SLC60 Glucose transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

3043

major facilitator superfamily domain containing 4A / SLC60A1 C Show summary »« Hide summary

Target Id	3043
Nomenclature	major facilitator superfamily domain containing 4A
Systematic nomenclature	SLC60A1
Previous and unofficial names	MFSD4
Genes	MFSD4A (Hs), Mfsd4a (Mm), Mfsd4a (Rn)
Ensembl ID	ENSG00000174514 (Hs), ENSMUSG00000059149 (Mm), ENSRNOG00000024657 (Rn)
UniProtKB AC	Q8N468 (Hs), Q6PDC8 (Mm)
RESOLUTE	MFSD4A (Hs)

major facilitator superfamily domain containing 4B / SLC60A2 C Show summary »« Hide summary

Target Id

3044

Nomenclature

major facilitator superfamily domain containing 4B

Systematic nomenclature

SLC60A2

Previous and unofficial names

Mfsd4b | KIAA1919 | NAGLT1

Genes

MFSD4B (Hs), Mfsd4b1 (Mm), Mfsd4b1 (Rn)

Ensembl ID

ENSG00000173214 (Hs), ENSMUSG00000038522 (Mm), ENSRNOG00000024543 (Rn)

UniProtKB AC

Q5TF39 (Hs), Q8VCV9 (Mm)

RESOLUTE

MFSD4B (Hs)

Transport type (Rat)

Co-transporter / Na⁺ (1:1) uptake [1]

Substrates

α-Me-glucose, D-glucose Rat [1]

Inhibitors

phloretin [1] - Rat

urea [2] - Rat

phlorizin [1] - Rat

Comment

Expressed in rat kidney (cortex and medulla), brain, liver and lung [1].

References

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How to cite this family page

Database page citation:

SLC60 Glucose transporters. Accessed on 24/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1012.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.

SLC60 Glucose transporters C

Transporters

Further reading

References

How to cite this family page