Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	1265	1q43	MTR	5-methyltetrahydrofolate-homocysteine methyltransferase	1
Mouse	-	1253	13 4.52 cM	Mtr	5-methyltetrahydrofolate-homocysteine methyltransferase
Rat	-	1253	17q12.1	Mtr	5-methyltetrahydrofolate-homocysteine methyltransferase

Previous and Unofficial Names

cblG | cobalamin-dependent methionine synthase | vitamin-B12 dependent methionine synthase

Database Links
Alphafold	Q99707 (Hs), A6H5Y3 (Mm), Q9Z2Q4 (Rn)
BRENDA	2.1.1.13
ChEMBL Target	CHEMBL2150844 (Hs), CHEMBL3188 (Mm)
Ensembl Gene	ENSG00000116984 (Hs), ENSMUSG00000021311 (Mm), ENSRNOG00000017593 (Rn)
Entrez Gene	4548 (Hs), 238505 (Mm), 81522 (Rn)
Human Protein Atlas	ENSG00000116984 (Hs)
KEGG Enzyme	2.1.1.13
KEGG Gene	hsa:4548 (Hs), mmu:238505 (Mm), rno:81522 (Rn)
OMIM	156570 (Hs)
Pharos	Q99707 (Hs)
RefSeq Nucleotide	NM_000254 (Hs), NM_001081128 (Mm), NM_030864 (Rn)
RefSeq Protein	NP_000245 (Hs), NP_001074597 (Mm), NP_110491 (Rn)
UniProtKB	Q99707 (Hs), A6H5Y3 (Mm), Q9Z2Q4 (Rn)
Wikipedia	MTR (Hs)

Enzyme Reaction
EC Number: 2.1.1.13 5-methyltetrahydrofolate + L-homocysteine <=> tetrahydrofolate + L-methionine

General Comments
MTR catalyses the final step in methionine biosynthesis.