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CINCA syndrome

Disease ID:1026
Name:CINCA syndrome
Associated with:1 target
1 immuno-relevant ligand
Chronic infantile neurological cutaneous articular syndrome
Database Links
OMIM: 607115
Orphanet: ORPHA1451




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Ligand References Clinical and Disease comments
Immuno Disease Comments: Approved drug for CINCA syndrome.
Clinical Use: Currently used in the treatment of cryopyrin-associated periodic syndrome (CAPS). Cryopyrin-associated periodic syndrome includes three previously distinct disorders: Familial cold autoinflammatory syndrome; Muckle-Wells syndrome; and CINCA syndrome, that are now considered to represent a disease continuum, all caused by NLRP3 protein mutations.

EMA approval has been withdrawn. | View clinical data