Fushi tarazu F1-like receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [1]) have yet to be officially paired with an endogenous ligand.

* Key recommended reading is highlighted with an asterisk

* Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V. (2006) International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol. Rev., 58 (4): 798-836. [PMID:17132856]

Büdefeld T, Tobet SA, Majdic G. (2012) Steroidogenic factor 1 and the central nervous system. J. Neuroendocrinol., 24 (1): 225-35. [PMID:21668533]

El-Khairi R, Martinez-Aguayo A, Ferraz-de-Souza B, Lin L, Achermann JC. (2011) Role of DAX-1 (NR0B1) and steroidogenic factor-1 (NR5A1) in human adrenal function. Endocr Dev, 20: 38-46. [PMID:21164257]

Fernandez-Marcos PJ, Auwerx J, Schoonjans K. (2011) Emerging actions of the nuclear receptor LRH-1 in the gut. Biochim. Biophys. Acta, 1812 (8): 947-55. [PMID:21194563]

Ferraz-de-Souza B, Lin L, Achermann JC. (2011) Steroidogenic factor-1 (SF-1, NR5A1) and human disease. Mol. Cell. Endocrinol., 336 (1-2): 198-205. [PMID:21078366]

* Garattini E, Bolis M, Gianni' M, Paroni G, Fratelli M, Terao M. (2016) Lipid-sensors, enigmatic-orphan and orphan nuclear receptors as therapeutic targets in breast-cancer. Oncotarget, 7 (27): 42661-42682. [PMID:26894976]

* Germain P, Staels B, Dacquet C, Spedding M, Laudet V. (2006) Overview of nomenclature of nuclear receptors. Pharmacol. Rev., 58 (4): 685-704. [PMID:17132848]

Huang P, Chandra V, Rastinejad F. (2010) Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics. Annu. Rev. Physiol., 72: 247-72. [PMID:20148675]

Lazarus KA, Wijayakumara D, Chand AL, Simpson ER, Clyne CD. (2012) Therapeutic potential of Liver Receptor Homolog-1 modulators. J. Steroid Biochem. Mol. Biol., 130 (3-5): 138-46. [PMID:22266285]

Młynarczuk J, Rękawiecki R. (2010) The role of the orphan receptor SF-1 in the development and function of the ovary. Reprod Biol, 10 (3): 177-93. [PMID:21113200]

Nadolny C, Dong X. (2015) Liver receptor homolog-1 (LRH-1): a potential therapeutic target for cancer. Cancer Biol. Ther., 16 (7): 997-1004. [PMID:25951367]

Schimmer BP, White PC. (2010) Minireview: steroidogenic factor 1: its roles in differentiation, development, and disease. Mol. Endocrinol., 24 (7): 1322-37. [PMID:20203099]

Sladek FM. (2011) What are nuclear receptor ligands?. Mol. Cell. Endocrinol., 334 (1-2): 3-13. [PMID:20615454]

* Zhi X, Zhou XE, Melcher K, Xu HE. (2016) Structures and regulation of non-X orphan nuclear receptors: A retinoid hypothesis. J. Steroid Biochem. Mol. Biol., 157: 27-40. [PMID:26159912]

* Zimmer V, Liebe R, Lammert F. (2015) Nuclear receptor variants in liver disease. Dig Dis, 33 (3): 415-9. [PMID:26045277]

1. Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V. (2006) International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol. Rev., 58 (4): 798-836. [PMID:17132856]

2. Del Tredici AL, Andersen CB, Currier EA, Ohrmund SR, Fairbain LC, Lund BW, Nash N, Olsson R, Piu F. (2008) Identification of the first synthetic steroidogenic factor 1 inverse agonists: pharmacological modulation of steroidogenic enzymes. Mol. Pharmacol., 73 (3): 900-8. [PMID:18055761]

3. Madoux F, Li X, Chase P, Zastrow G, Cameron MD, Conkright JJ, Griffin PR, Thacher S, Hodder P. (2008) Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening. Mol. Pharmacol., 73 (6): 1776-84. [PMID:18334597]