Cu<sup>+</sup>-ATPases | Transporters | IUPHAR/BPS Guide to PHARMACOLOGY

Cu⁺-ATPases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Copper-transporting ATPases convey copper ions across cell-surface and intracellular membranes. They consist of eight TM domains and associate with multiple copper chaperone proteins (e.g. ATOX1, O00244).

Transporters

ATP7A Show summary »« Hide summary

Target Id

852

Nomenclature

ATP7A

Previous and unofficial names

Genes

ATP7A (Hs), Atp7a (Mm), Atp7a (Rn)

Ensembl ID

ENSG00000165240 (Hs), ENSMUSG00000033792 (Mm), ENSRNOG00000002515 (Rn)

UniProtKB AC

Q04656 (Hs), Q64430 (Mm), P70705 (Rn)

EC number

3.6.3.4

ATP7B Show summary »« Hide summary

Target Id

853

Nomenclature

ATP7B

Previous and unofficial names

Genes

ATP7B (Hs), Atp7b (Mm), Atp7b (Rn)

Ensembl ID

ENSG00000123191 (Hs), ENSMUSG00000006567 (Mm), ENSRNOG00000012878 (Rn)

UniProtKB AC

P35670 (Hs), Q64446 (Mm), Q64535 (Rn)

EC number

3.6.3.4

How to cite this family page

Database page citation:

Cu⁺-ATPases. Accessed on 05/12/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=161.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Transporters. Br J Pharmacol. 176 Issue S1: S397-S493.

Cu+-ATPases C

Overview

Transporters

How to cite this family page

Cu⁺-ATPases C