Anion exchangers | Transporters | IUPHAR/BPS Guide to PHARMACOLOGY

Anion exchangers C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

AE1 (Anion exchange protein 1 / SLC4A1) C Show summary »« Hide summary

Target Id

904

Nomenclature

Anion exchange protein 1

Systematic nomenclature

SLC4A1

Common abbreviation

AE1

Previous and unofficial names

Genes

SLC4A1 (Hs), Slc4a1 (Mm), Slc4a1 (Rn)

Ensembl ID

ENSG00000004939 (Hs), ENSMUSG00000006574 (Mm), ENSRNOG00000020951 (Rn)

UniProtKB AC

P02730 (Hs), P04919 (Mm), P23562 (Rn)

Bioparadigms SLC Tables

SLC4A1 (Hs)

RESOLUTE

SLC4A1 (Hs)

Endogenous substrates

Cl^-

HCO₃^-

Stoichiometry

1 Cl^- (in) : 1 HCO₃^- (out)

AE2 (Anion exchange protein 2 / SLC4A2) C Show summary »« Hide summary

Target Id

905

Nomenclature

Anion exchange protein 2

Systematic nomenclature

SLC4A2

Common abbreviation

AE2

Previous and unofficial names

Genes

SLC4A2 (Hs), Slc4a2 (Mm), Slc4a2 (Rn)

Ensembl ID

ENSG00000164889 (Hs), ENSMUSG00000028962 (Mm), ENSRNOG00000014347 (Rn)

UniProtKB AC

P04920 (Hs), P13808 (Mm), P23347 (Rn)

Bioparadigms SLC Tables

SLC4A2 (Hs)

RESOLUTE

SLC4A2 (Hs)

Endogenous substrates

Cl^-

HCO₃^-

Stoichiometry

1 Cl^- (in) : 1 HCO₃^- (out)

AE3 (Anion exchange protein 3 / SLC4A3) C Show summary »« Hide summary

Target Id

906

Nomenclature

Anion exchange protein 3

Systematic nomenclature

SLC4A3

Common abbreviation

AE3

Previous and unofficial names

Genes

SLC4A3 (Hs), Slc4a3 (Mm), Slc4a3 (Rn)

Ensembl ID

ENSG00000114923 (Hs), ENSMUSG00000006576 (Mm), ENSRNOG00000020138 (Rn)

UniProtKB AC

P48751 (Hs), P16283 (Mm), P23348 (Rn)

Bioparadigms SLC Tables

SLC4A3 (Hs)

RESOLUTE

SLC4A3 (Hs)

Endogenous substrates

Cl^-

HCO₃^-

Stoichiometry

1 Cl^- (in) : 1 HCO₃^- (out)

AE4 (Anion exchange protein 4 / SLC4A9) C Show summary »« Hide summary

Target Id	907
Nomenclature	Anion exchange protein 4
Systematic nomenclature	SLC4A9
Common abbreviation	AE4
Previous and unofficial names	Sodium bicarbonate cotransporter 5 \| anion exchange protein 4 \| anion exchanger 4 \| solute carrier family 4 member 9 \| solute carrier family 4, sodium bicarbonate cotransporter, member 9 \| solute carrier family 4
Genes	SLC4A9 (Hs), Slc4a9 (Mm), Slc4a9 (Rn)
Ensembl ID	ENSG00000113073 (Hs), ENSMUSG00000024485 (Mm), ENSRNOG00000018525 (Rn)
UniProtKB AC	Q96Q91 (Hs), Q8K4V2 (Rn)
Bioparadigms SLC Tables	SLC4A9 (Hs)
RESOLUTE	SLC4A9 (Hs)

How to cite this family page

Database page citation:

Anion exchangers. Accessed on 26/01/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=170.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.