Sodium-dependent HCO<sub>3</sub><sup>-</sup> transporters | Transporters

Sodium-dependent HCO₃^- transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

NBCe1 (Electrogenic sodium bicarbonate cotransporter 1 / SLC4A4) C Show summary »« Hide summary

Target Id

908

Nomenclature

Electrogenic sodium bicarbonate cotransporter 1

Systematic nomenclature

SLC4A4

Common abbreviation

NBCe1

Previous and unofficial names

Genes

SLC4A4 (Hs), Slc4a4 (Mm), Slc4a4 (Rn)

Ensembl ID

ENSG00000080493 (Hs), ENSMUSG00000060961 (Mm), ENSRNOG00000003134 (Rn)

UniProtKB AC

Q9Y6R1 (Hs), O88343 (Mm), Q9JI66 (Rn)

Bioparadigms SLC Tables

SLC4A4 (Hs)

RESOLUTE

SLC4A4 (Hs)

Endogenous substrates

NaHCO₃

Stoichiometry

1 Na⁺ : 2/3 HCO₃^- (out) or 1 Na⁺ : CO₃^2*

NBCe2 (Electrogenic sodium bicarbonate cotransporter 4 / SLC4A5) C Show summary »« Hide summary

Target Id

909

Nomenclature

Electrogenic sodium bicarbonate cotransporter 4

Systematic nomenclature

SLC4A5

Common abbreviation

NBCe2

Previous and unofficial names

Genes

SLC4A5 (Hs), Slc4a5 (Mm), Slc4a5 (Rn)

Ensembl ID

ENSG00000188687 (Hs), ENSMUSG00000068323 (Mm), ENSRNOG00000010378 (Rn)

UniProtKB AC

Q9BY07 (Hs), Q6RI88 (Rn)

Bioparadigms SLC Tables

SLC4A5 (Hs)

RESOLUTE

SLC4A5 (Hs)

Endogenous substrates

NaHCO₃

Stoichiometry

1 Na⁺ : 2/3 HCO₃^- (out) or 1 Na⁺ : CO₃^2*

NBCn1 (Electroneutral sodium bicarbonate cotransporter 1 / SLC4A7) C Show summary »« Hide summary

Target Id

910

Nomenclature

Electroneutral sodium bicarbonate cotransporter 1

Systematic nomenclature

SLC4A7

Common abbreviation

NBCn1

Previous and unofficial names

Genes

SLC4A7 (Hs), Slc4a7 (Mm), Slc4a7 (Rn)

Ensembl ID

ENSG00000033867 (Hs), ENSMUSG00000021733 (Mm), ENSRNOG00000005957 (Rn)

UniProtKB AC

Q9Y6M7 (Hs), Q8BTY2 (Mm), Q9R1N3 (Rn)

Bioparadigms SLC Tables

SLC4A7 (Hs)

RESOLUTE

SLC4A7 (Hs)

Endogenous substrates

NaHCO₃

Stoichiometry

1 Na⁺ : 1 HCO₃^- (out) or 1 Na⁺ : CO₃^2*

NBCn2 (Electroneutral sodium bicarbonate cotransporter 2 / SLC4A10) C Show summary »« Hide summary

Target Id

911

Nomenclature

Electroneutral sodium bicarbonate cotransporter 2

Systematic nomenclature

SLC4A10

Common abbreviation

NBCn2

Previous and unofficial names

NCBE | solute carrier family 4, sodium bicarbonate transporter-like, member 10 | solute carrier family 4 member 10 | solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 | solute carrier family 4

Genes

SLC4A10 (Hs), Slc4a10 (Mm), Slc4a10 (Rn)

Ensembl ID

ENSG00000144290 (Hs), ENSMUSG00000026904 (Mm), ENSRNOG00000005307 (Rn)

UniProtKB AC

Q6U841 (Hs), Q5DTL9 (Mm), Q80ZA5 (Rn)

Bioparadigms SLC Tables

SLC4A10 (Hs)

RESOLUTE

SLC4A10 (Hs)

Endogenous substrates

NaHCO₃

Stoichiometry

1 Na⁺ : 1 HCO₃^- (out) or 1 Na : CO₃^2*

NDCBE (NBCBE / SLC4A8) C Show summary »« Hide summary

Target Id

912

Nomenclature

NBCBE

Systematic nomenclature

SLC4A8

Common abbreviation

NDCBE

Previous and unofficial names

Genes

SLC4A8 (Hs), Slc4a8 (Mm), Slc4a8 (Rn)

Ensembl ID

ENSG00000050438 (Hs), ENSMUSG00000023032 (Mm), ENSRNOG00000028879 (Rn)

UniProtKB AC

Q2Y0W8 (Hs), Q8JZR6 (Mm), Q6RVG2 (Rn)

Bioparadigms SLC Tables

SLC4A8 (Hs)

RESOLUTE

SLC4A8 (Hs)

Endogenous substrates

Cl^-

NaHCO₃

Stoichiometry

1 Na⁺ : 2HCO₃^- (in) : 1 Cl^- (out)

BTR1 (NaBC1 / SLC4A11) C Show summary »« Hide summary

Target Id

913

Nomenclature

NaBC1

Systematic nomenclature

SLC4A11

Common abbreviation

BTR1

Previous and unofficial names

Genes

SLC4A11 (Hs), Slc4a11 (Mm), Slc4a11 (Rn)

Ensembl ID

ENSG00000088836 (Hs), ENSMUSG00000074796 (Mm), ENSRNOG00000021234 (Rn)

UniProtKB AC

Q8NBS3 (Hs), A2AJN7 (Mm)

Bioparadigms SLC Tables

SLC4A11 (Hs)

RESOLUTE

SLC4A11 (Hs)

Endogenous substrates

Cl^-

NaHCO₃

How to cite this family page

Database page citation:

Sodium-dependent HCO₃^- transporters. Accessed on 19/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=171.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.

Sodium-dependent HCO3- transporters C

Transporters

How to cite this family page

Sodium-dependent HCO₃^- transporters C