Chloride/bicarbonate exchangers | Transporters | IUPHAR/BPS Guide to PHARMACOLOGY

Chloride/bicarbonate exchangers C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

DRA / SLC26A3 C Show summary »« Hide summary

Target Id

1099

Nomenclature

DRA

Systematic nomenclature

SLC26A3

Previous and unofficial names

Genes

SLC26A3 (Hs), Slc26a3 (Mm), Slc26a3 (Rn)

Ensembl ID

ENSG00000091138 (Hs), ENSMUSG00000001225 (Mm), ENSRNOG00000006878 (Rn)

UniProtKB AC

P40879 (Hs), Q9WVC8 (Mm), Q924C9 (Rn)

Bioparadigms SLC Tables

SLC26A3 (Hs)

RESOLUTE

SLC26A3 (Hs)

Substrates

Cl^-

Stoichiometry

2 Cl^- (in) : 1 HCO₃^- (out) or 2 Cl^- (in) : 1 OH^- (out)

Pendrin / SLC26A4 C Show summary »« Hide summary

Target Id

1100

Nomenclature

Pendrin

Systematic nomenclature

SLC26A4

Previous and unofficial names

Genes

SLC26A4 (Hs), Slc26a4 (Mm), Slc26a4 (Rn)

Ensembl ID

ENSG00000091137 (Hs), ENSMUSG00000020651 (Mm), ENSRNOG00000058692 (Rn)

UniProtKB AC

O43511 (Hs), Q9R155 (Mm), Q9R154 (Rn)

Bioparadigms SLC Tables

SLC26A4 (Hs)

RESOLUTE

SLC26A4 (Hs)

Substrates

Cl^-

formate

HCO₃^-

I^-

OH^-

Stoichiometry

Unknown

PAT-1 / SLC26A6 C Show summary »« Hide summary

Target Id

1101

Nomenclature

PAT-1

Systematic nomenclature

SLC26A6

Previous and unofficial names

Genes

SLC26A6 (Hs), Slc26a6 (Mm), Slc26a6 (Rn)

Ensembl ID

ENSG00000225697 (Hs), ENSMUSG00000023259 (Mm), ENSRNOG00000020450 (Rn)

UniProtKB AC

Q9BXS9 (Hs)

Bioparadigms SLC Tables

SLC26A6 (Hs)

RESOLUTE

SLC26A6 (Hs)

Substrates

Cl^-

oxalate

formate

HCO₃^-

I^-

OH^-

SO₄^2-

Stoichiometry

1 SO₄^2- (in) : 2 HCO₃^- (out) or 1 Cl^- (in) : 2 HCO₃^- (out)

How to cite this family page

Database page citation:

Chloride/bicarbonate exchangers. Accessed on 12/06/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=211.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.