Arginine:glycine amidinotransferase | Enzymes | IUPHAR/BPS Guide to PHARMACOLOGY

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L-Arginine turnover
Arginine:glycine amidinotransferase

Arginine:glycine amidinotransferase C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Arginine:glycine amidinotransferase is a mitochondrial enzyme that is involved in creatine biosynthesis.

Enzymes

AGAT (Arginine:glycine amidinotransferase) C Show summary »« Hide summary

Target Id

1246

Nomenclature

Arginine:glycine amidinotransferase

Common abbreviation

AGAT

Previous and unofficial names

GATM | AT | glycine amidinotransferase, mitochondrial | transamidinase | glycine amidinotransferase (L-arginine:glycine amidinotransferase)

Genes

GATM (Hs), Gatm (Mm), Gatm (Rn)

Ensembl ID

ENSG00000171766 (Hs), ENSMUSG00000027199 (Mm), ENSRNOG00000000168 (Rn)

UniProtKB AC

P50440 (Hs), Q9D964 (Mm), P50442 (Rn)

EC number

2.1.4.1

Comments

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How to cite this family page

Database page citation:

Arginine:glycine amidinotransferase. Accessed on 08/07/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=251.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.