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IL-3 receptor family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The IL-3 receptor family signal through a receptor complex comprising of a ligand-specific α subunit and a common β chain (CSF2RB, P32927), which is associated with Jak2 and signals primarily through Stat5.

Receptors

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Complexes

Interleukin-3 receptor C Show summary » More detailed page go icon to follow link

Interleukin-5 receptor C Show summary » More detailed page go icon to follow link

Granulocyte macrophage colony-stimulating factor receptor C Show summary » More detailed page go icon to follow link

Receptors and Subunits

Interleukin 3 receptor, α subunit C Show summary » More detailed page go icon to follow link

Interleukin 5 receptor, α subunit C Show summary » More detailed page go icon to follow link

GM-CSF receptor, α subunit C Show summary » More detailed page go icon to follow link

Cytokine receptor common β subunit C Show summary » More detailed page go icon to follow link

Further reading

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References

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How to cite this family page

Database page citation:

IL-3 receptor family. Accessed on 08/12/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=306.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors. Br J Pharmacol. 178 Suppl 1:S264-S312.