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IL-12 receptor family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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IL-12 receptors are a subfamily of the IL-6 receptor family. IL12RB1 is shared between receptors for IL-12 and IL-23; the functional agonist at IL-12 receptors is a heterodimer of IL-12A/IL-12B, while that for IL-23 receptors is a heterodimer of IL-12B/IL-23A.

Receptors

Complexes

Interleukin-12 receptor C Show summary » More detailed page

Interleukin-23 receptor C Show summary » More detailed page

Receptors and Subunits

Interleukin-12 receptor, β1 subunit C Show summary » More detailed page

Interleukin-12 receptor, β2 subunit C Show summary » More detailed page

Interleukin 23 receptor C Show summary » More detailed page

Further reading

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How to cite this family page

Database page citation:

IL-12 receptor family. Accessed on 15/12/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=308.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Catalytic receptors. Br J Pharmacol. 176 Suppl 1: S247-S296.