NIMA (never in mitosis gene a)- related kinase (NEK) family

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NIMA (never in mitosis gene a)- related kinase (NEK) family

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

NEK1 (NIMA related kinase 1) Show summary »« Hide summary More detailed page go icon to follow link

NEK2 (NIMA related kinase 2) Show summary »« Hide summary More detailed page go icon to follow link

NEK3 (NIMA related kinase 3) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2118

Nomenclature

NIMA related kinase 3

Common abbreviation

NEK3

Previous and unofficial names

HSPK36 | phosphorylase B kinase kinase | NIMA-related kinase 3

Genes

NEK3 (Hs), Nek3 (Mm), Nek3 (Rn)

Ensembl ID

ENSG00000136098 (Hs), ENSMUSG00000031478 (Mm), ENSRNOG00000012757 (Rn)

UniProtKB AC

P51956 (Hs), Q9R0A5 (Mm)

EC number

2.7.11.1

NEK4 (NIMA related kinase 4) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2119

Nomenclature

NIMA related kinase 4

Common abbreviation

NEK4

Previous and unofficial names

NRK2 | serine/threonine protein kinase-2 | STK2 | NIMA-related kinase 4

Genes

NEK4 (Hs), Nek4 (Mm), Nek4 (Rn)

Ensembl ID

ENSG00000114904 (Hs), ENSMUSG00000021918 (Mm), ENSRNOG00000017997 (Rn)

UniProtKB AC

P51957 (Hs), Q9Z1J2 (Mm)

EC number

2.7.11.1

NEK5 (NIMA related kinase 5) Show summary »« Hide summary More detailed page go icon to follow link

NEK6 (NIMA related kinase 6) Show summary »« Hide summary More detailed page go icon to follow link

NEK7 (NIMA related kinase 7) Show summary »« Hide summary More detailed page go icon to follow link

NEK8 (NIMA related kinase 8) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2123

Nomenclature

NIMA related kinase 8

Common abbreviation

NEK8

Previous and unofficial names

ANPHP9 | JCK | NEK12A | Nima-related protein kinase 12a | NIMA-related kinase 8

Genes

NEK8 (Hs), Nek8 (Mm), Nek8 (Rn)

Ensembl ID

ENSG00000160602 (Hs), ENSMUSG00000017405 (Mm), ENSRNOG00000012866 (Rn)

UniProtKB AC

Q86SG6 (Hs), Q91ZR4 (Mm)

EC number

2.7.11.1

NEK9 (NIMA related kinase 9) Show summary »« Hide summary More detailed page go icon to follow link

NEK10 (NIMA related kinase 10) Show summary »« Hide summary More detailed page go icon to follow link

NEK11 (NIMA related kinase 11) Show summary »« Hide summary More detailed page go icon to follow link

References

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How to cite this family page

Database page citation:

NIMA (never in mitosis gene a)- related kinase (NEK) family. Accessed on 08/07/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=588.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.