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M12: Astacin/Adamalysin C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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ADAM (A Disintegrin And Metalloproteinase domain containing proteins) metalloproteinases cleave cell-surface or transmembrane proteins to generate soluble and membrane-limited products.

ADAMTS (with thrombospondin motifs) metalloproteinases cleave cell-surface or transmembrane proteins to generate soluble and membrane-limited products.

Enzymes

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ADAM2 Show summary »

ADAM7 Show summary »

ADAM8 Show summary » More detailed page go icon to follow link

ADAM9 Show summary » More detailed page go icon to follow link

ADAM10 Show summary » More detailed page go icon to follow link

ADAM11 Show summary »

ADAM12 Show summary » More detailed page go icon to follow link

ADAM15 Show summary »

ADAM17 Show summary » More detailed page go icon to follow link

ADAM18 Show summary »

ADAM19 Show summary »

ADAM20 Show summary »

ADAM21 Show summary »

ADAM22 Show summary »

ADAM23 Show summary »

ADAM28 Show summary »

ADAM29 Show summary »

ADAM30 Show summary »

ADAM32 Show summary »

ADAM33 Show summary » More detailed page go icon to follow link

ADAMTS1 Show summary » More detailed page go icon to follow link

ADAMTS2 Show summary »

ADAMTS3 Show summary »

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ADAMTS5 Show summary » More detailed page go icon to follow link

ADAMTS6 Show summary »

ADAMTS7 Show summary »

ADAMTS8 Show summary »

ADAMTS9 Show summary »

ADAMTS10 Show summary »

ADAMTS12 Show summary »

ADAMTS13 Show summary »

ADAMTS14 Show summary »

ADAMTS15 Show summary »

ADAMTS16 Show summary »

ADAMTS17 Show summary »

ADAMTS18 Show summary »

ADAMTS19 Show summary »

ADAMTS20 Show summary »

bone morphogenetic protein 1 Show summary » More detailed page go icon to follow link

Comments

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References

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How to cite this family page

Database page citation:

M12: Astacin/Adamalysin. Accessed on 20/06/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=739.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.