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Non-enzymatic BRD containing proteins C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Bromodomains bind proteins with acetylated lysine residues, such as histones, to regulate gene transcription. Listed herein are examples of bromodomain-containing proteins for which sufficient pharmacology exists.

Targets

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bromodomain adjacent to zinc finger domain 1A Show summary » More detailed page go icon to follow link

bromodomain adjacent to zinc finger domain 1B Show summary » More detailed page go icon to follow link

bromodomain adjacent to zinc finger domain 2A C Show summary » More detailed page go icon to follow link

bromodomain adjacent to zinc finger domain 2B C Show summary » More detailed page go icon to follow link

bromodomain PHD finger transcription factor Show summary » More detailed page go icon to follow link

bromodomain testis associated Show summary » More detailed page go icon to follow link

bromodomain and PHD finger containing 1 Show summary » More detailed page go icon to follow link

bromodomain and PHD finger containing 3 Show summary » More detailed page go icon to follow link

bromodomain and WD repeat domain containing 1 Show summary » More detailed page go icon to follow link

bromodomain and WD repeat domain containing 3 Show summary » More detailed page go icon to follow link

CECR2 histone acetyl-lysine reader Show summary » More detailed page go icon to follow link

CREB binding protein C Show summary » More detailed page go icon to follow link

E1A binding protein p300 Show summary » More detailed page go icon to follow link

polybromo 1 C Show summary » More detailed page go icon to follow link

SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) Show summary » More detailed page go icon to follow link

SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4) C Show summary » More detailed page go icon to follow link

pleckstrin homology domain interacting protein Show summary » More detailed page go icon to follow link

SP100 nuclear antigen Show summary » More detailed page go icon to follow link

SP110 nuclear body protein Show summary » More detailed page go icon to follow link

SP140 nuclear body protein Show summary » More detailed page go icon to follow link

SP140 nuclear body protein like Show summary » More detailed page go icon to follow link

zinc finger MYND-type containing 8 Show summary » More detailed page go icon to follow link

zinc finger MYND-type containing 11 Show summary » More detailed page go icon to follow link

tripartite motif containing 66 Show summary » More detailed page go icon to follow link

Further reading

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References

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How to cite this family page

Database page citation:

Non-enzymatic BRD containing proteins. Accessed on 04/12/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=867.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. Br J Pharmacol. 178 Suppl 1:S1-S26.