1.17.4.1 Ribonucleoside-diphosphate reductases

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1.17.4.1 Ribonucleoside-diphosphate reductases

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

ribonucleotide reductase M1 (ribonucleotide reductase catalytic subunit M1) C Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2630

Nomenclature

ribonucleotide reductase catalytic subunit M1

Common abbreviation

ribonucleotide reductase M1

Previous and unofficial names

ribonucleoside-diphosphate reductase large subunit | ribonucleotide reductase M1

Genes

RRM1 (Hs), Rrm1 (Mm), Rrm1 (Rn)

Ensembl ID

ENSG00000167325 (Hs), ENSMUSG00000030978 (Mm), ENSRNOG00000045752 (Rn)

UniProtKB AC

P23921 (Hs), P07742 (Mm)

EC number

1.17.14.1

ribonucleotide reductase M2 (ribonucleotide reductase regulatory subunit M2) C Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2631

Nomenclature

ribonucleotide reductase regulatory subunit M2

Common abbreviation

ribonucleotide reductase M2

Previous and unofficial names

ribonucleoside-diphosphate reductase subunit | Rrm2 | ribonucleotide reductase M2

Genes

RRM2 (Hs), Rrm2 (Mm), Rrm2 (Rn)

Ensembl ID

ENSG00000171848 (Hs), ENSMUSG00000020649 (Mm), ENSRNOG00000054286 (Rn)

UniProtKB AC

P31350 (Hs), P11157 (Mm), Q4KLN6 (Rn)

EC number

1.17.4.1

ribonucleotide reductase M2B (TP53 inducible) (ribonucleotide reductase regulatory TP53 inducible subunit M2B) C Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2754

Nomenclature

ribonucleotide reductase regulatory TP53 inducible subunit M2B

Common abbreviation

ribonucleotide reductase M2B (TP53 inducible)

Previous and unofficial names

ribonucleotide reductase M2 B (TP53 inducible)

Genes

RRM2B (Hs), Rrm2b (Mm), Rrm2b (Rn)

Ensembl ID

ENSG00000048392 (Hs), ENSMUSG00000022292 (Mm), ENSRNOG00000025454 (Rn)

UniProtKB AC

Q7LG56 (Hs), Q6PEE3 (Mm)

EC number

1.17.1.4

How to cite this family page

Database page citation:

1.17.4.1 Ribonucleoside-diphosphate reductases. Accessed on 07/10/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=877.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.