Purine-nucleoside phosphorylase

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Purine-nucleoside phosphorylase

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

PNP (purine nucleoside phosphorylase) C Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2841

Nomenclature

purine nucleoside phosphorylase

Common abbreviation

PNP

Previous and unofficial names

NP | nucleoside phosphorylase | PUNP

Genes

PNP (Hs), Pnp (Mm), Pnp (Rn)

Ensembl ID

ENSG00000198805 (Hs), ENSMUSG00000115338 (Mm), ENSRNOG00000009982 (Rn)

UniProtKB AC

P00491 (Hs), P23492 (Mm), P85973 (Rn)

EC number

1.4.2.1
Purine-nucleoside phosphorylase Purine nucleoside + phosphate <=> purine + alpha-D-ribose 1-phosphate Purine deoxynucleoside + phosphate <=> purine + 2'-deoxy-alpha-D-ribose 1-phosphate

How to cite this family page

Database page citation:

Purine-nucleoside phosphorylase. Accessed on 14/08/2026. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=908.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Gibb AJ, Kelly E, Mathie AA, Peach CJ, Veale EL, Armstrong JF, Faccenda E, Harding SD, Southan C, Davies JA et al. (2025) The Concise Guide to PHARMACOLOGY 2025/26: Enzymes. Br J Pharmacol. 182: S307-S403.