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C-type lectin-like receptors (CLRs)

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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C-type lectin-like receptors are single-pass type II membrane proteins involved widely in the recognition of pathogens and initiation of the innate response to maintain immune homeostasis [1-2].

Targets

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DCIR (C-type lectin domain family 4 member A) Show summary » More detailed page go icon to follow link

BDCA2 (C-type lectin domain family 4 member C) Show summary » More detailed page go icon to follow link

DC-SIGN (CD209 molecule) Show summary » More detailed page go icon to follow link

Dectin-1 (C-type lectin domain family 7 member A) Show summary » More detailed page go icon to follow link

Dectin-2 (C-type lectin domain family 6 member A) Show summary » More detailed page go icon to follow link

Mincle (C-type lectin domain family 4 member E) Show summary » More detailed page go icon to follow link

C-type lectin domain family 12 member A / CD371 Show summary » More detailed page go icon to follow link

References

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How to cite this family page

Database page citation:

C-type lectin-like receptors (CLRs). Accessed on 22/09/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=945.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. Br J Pharmacol. 176 Issue S1: S1-S20.