Top ▲

Immune checkpoint proteins

Overview

« Hide More detailed introduction

Immune checkpoint pathway blockade has revolutionized cancer treatment for some patients, with targeted immunotherapies including ipilimumab, pembrolizumab, nivolumab, atezolizumab, durvalumab, and avelumab making it to the clinic.

Subfamilies

How to cite this family page

Database page citation:

Immune checkpoint proteins. Accessed on 16/12/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=954.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. Br J Pharmacol. 176 Issue S1: S1-S20.